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Biomedical subjects

M Englert

Publications and source records attributed to M Englert.

31 records · Page 2Linked to original sources
PubMed1976

Static mechanical lung properties in healthy children.

The elastic properties of the lung (elastic recoil and static compliance) have been studied in 27 children from 7 to 15 years of age by a quasi-static method. There is a significant relationship between the static expiratory compliance and the quasistatic pressures at different percentages of total lung capacity on the one hand, and height and age on the other. The specific compliance is independent of both height and age. The authors also use a sigmoid mathematical model based on the relationship between specific compliance and maximum pulmonary volume. This model fits well with the experimental data. Comparison is made with the currently used exponential model of Salazar & Knowles. The results favour the hypothesis of an increase in the number of alveoli all through childhood.

Adolescent↗
PubMed1975

A sigmoid model of the static volume-pressure curve of human lung.

The authors present a sigmoid mathematical model of the pressure-volume curve of the human lung, based on a relationship between the specific compliance and the maximal pulmonary volume: (see article). This model fits better the experimental data obtained in 20 young normal adults than the currently used exponential model of Salazar and Knowles (1964). The independence between the constant K' and body height is interpreted as a constancy of pulmonary structure for normal subjects of the same age range.

Adult↗
PubMed1975

Pulmonary mechanics and diffusion after 'shock lung'.

Pulmonary function studies performed in seven patients who had recovered from 'shock lung' showed a highly significant decrease of diffusing properties of the lung, a slight loss of lung recoil pressure, and a borderline increase of residual volume with normal vital capacity and total lung capacity. Pulmonary compliance was normal. The interpretation of these findings is discussed.

Acute Disease↗
PubMed1975

Pulmonary function in metastatic carcinoma to the lung.

Pulmonary function tests, at rest and during exercise, were performed in nine patients with metastatic carcinoma to the lung. The results are compared to the usual characteristics of diffuse interstitial fibrosis. Differences also occur between the pure multiple metastases pattern and the lymphangitic one. Literature on this topic is reviewed.

Adult↗
PubMed1975

[Regional distribution of ventilation and perfusion in the beginning chronic bronchopneumopathies].

The regional distribution of lung ventilation and perfusion was determined in five normal subjects and in patients suffering from chronic bronchitis or asthma with variable functional repercussion, and also in some cases of beginning lung emphysema. The system of detection under use is a scanning camera coupled with a computer. In the case of chronic bronchitis or of asthma, there exists, the more often, a redistribution of lung ventilation and perfusion from the bases towards the vertices. The alterations are less evident in the cases of emphysema submitted to study. The limits of the method are object of discussion. Its application to the early detection of bronchopneumopathies does not appear as possible.

Adult↗
PubMedDate not supplied

Pulmonary mechanics in diffuse fibrosing alveolitis.

The mechanical and the diffusing lung properties have been measured in 19 cases of diffuse fibrosing alveolitis of unknown etiology (proved by histology in 17 cases). The characteristic findings are: a) a striking reduction of DLCO in all the cases; b) a marked reduction of the static and dynamic compliance, in correlation with the reduction of vital capacity; c) an increase in P1max in correlation with the decrease of FRC; d) an increase of the elastic recoil when it is considered at various percentages of the predicted lung volume, but in some cases a normal shape of the V-P curve if the measured lung volume is taken into account; e) a reduction of the maximum expiratory flows suggesting bronchiolar stenosis; f) alterations of DL more marked than those of CL suggesting that DL is a more sensitive test.

Adult↗
PubMedDate not supplied

Effect of growth and aging on the static mechanical lung properties.

Quasi-static expiratory pressure-volume curves were obtained in 119 healthy subjects 7 to 64 years old. Lung recoil pressures were measured at six fixed percentages of TLC between 100 percent and 50 percent. In children and adolescents lung recoil pressures increased with growth till about the age of fifteen and there were no differences between sexes. In adults less than 40 years old there was also no sex difference in lung recoil pressures, whereas in subjects more than 40 years old, females had lower recoil pressures than males at every level of TLC. Both in males and females, aging is associated with a marked decrease of lung recoil pressures. Smoking had no detectable effect on lung recoil in males. During growth the evolution of static compliance was closely related to height, whereas in adults this relationship was less evident particularly in males. There was no sex differences in specific compliance which tended to increase slightly with aging.

Adolescent↗
PubMedDate not supplied

Follow-up of pulmonary function after "shock lung".

Long-term follow-up of pulmonary function has been performed in four patients having recovered from "shock lung". In three patients there is a progressive normalization of lung volumes and lung compliance, whereas the pulmonary diffusing capacity improves but without attaining predicted levels. In the fourth patient, a delayed reduction of total lung capacity, lung compliance and diffusion capacity occurred. During the follow-up period (from one month to four years) there was no complaint and physical examination, electrocardiogram, chest roentgenogram, conventional pulmonary perfusion scintigraphy and arterial blood gases at rest were quite normal. These results are compatible with the persistence of some degree of interstitial lung disease after recovery from "shock lung".

Adult↗