Biomedical subjects
Publications and source records attributed to M Ermete.
A 32-year-old male presented with a mass in the parotid gland. Superficial parotidectomy was performed. Histopathologically the tumour was found to be schwannoma (neurilemmoma) and because this is unusual, the case is presented together with the histopathological findings.
A 47-year-old woman presented with slightly pruritic, burning lesions on her submammary area and legs of 3.5 years' duration. Similar lesions had appeared on her arms and feet. She was hospitalized at the Pulmonary Diseases Hospital, Izmir, with a complaint of thoracic pain, and was diagnosed with nonspecific pleuritis by pulmonary X-ray, thoracic computed tomography (CT) scanning, bacterial cultures of phlegm, and pleural biopsy examination. Fifteen days after leaving hospital, she was admitted to the Surgical Clinic of Atatürk Training Hospital, Izmir, with a complaint of severe abdominal pain, and diagnosed with nonspecific peritonitis. On dermatologic examination, she had multiple, scattered papules (2-3 mm in diameter), with a typical, central, white, porcelain-like zone of atrophy, on the trunk (Fig. 1), legs (Fig. 2), and arms. The lesions were encircled by a slightly raised erythematous border. Some of the lesions had coalesced giving polycyclic atrophic areas and ulcerations. Histopathologic examination of the skin biopsy specimen showed hyperkeratosis, epidermal atrophy, dermo-epidermal separation, edema, and necrosis in the papillary dermis (Fig. 3). Fibrinoid necrosis and thrombosis were seen in the papillary dermis and in the vessels below the lesions. The patient was diagnosed with Degos' disease from these clinical and histopathologic findings. She was treated with anti-inflammatory drugs. One year later, the patient was hospitalized at the Department of Internal Medicine of Atatürk Training Hospital, Izmir, with a diagnosis of pericarditis and pleuritis.
We present a case of large, primary malignant melanoma of the female urethra with poor prognosis in this case report. Malignant melanoma is one of the rare tumors of the female urethra and accounts for 0.2% of all malignant melanoma cases. Large (5.6 cm in diameter), primary malignant melanoma of the female urethra is exceedingly rare.
Specimens from 40 cases of thyroid carcinomas, including 35 papillary, 2 follicular, 2 undifferentiated, and 1 Hurtle cell carcinoma were analyzed for neuroendocrine differentiation with immunohistochemical tests for synapthophysin, neuron-specific enolase (NSE), chromogranin, and calcitonin; all cases were stained for thyroglobulin. Histologically, none of the cases resembled a medullary carcinoma. Twenty-five percent (10 cases) were immunoreactive for one, 30% (12 cases) for two, and 15% (6 cases) for three markers. Three of the cases that were positive for all 3 markers (7.5% of all total) had diffuse strong immunoreactivity. These results demonstrated neuroendocrine differentiation may occur in non-neuroendocrine thyroid tumors and may support the postulation that endodermally derived ultimobronchial stem cells might give rise to C cells as well as follicular cells.
A 36-year-old patient with a primary leiomyosarcoma of the left parotid gland is presented. To our knowledge this is only the second case of a parotid leiomyosarcoma in the world according to the literature review.