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M Erminy

Publications and source records attributed to M Erminy.

11 recordsLinked to original sources
PubMed1998

Characteristics of the acoustic distortion product 2f2-f1 from the normal human ear.

The aim of this study was to determine the basic properties of the 2f2-f1 distortion product otoacoustic emissions (DPOEs) in 36 normally hearing subjects and to compare their characteristics with those of the 2f1-f2 DPOEs. The influence of stimulation parameters on 2f2-f1 DPOE behaviour was examined: i) stimulation levels varied from 40 to 70 dB sound pressure level in 10 dB steps; and ii) two values of the f2/f1 ratio were used (1.12 and 1.22). The prevalence and the level of the 2f2-f1 DPOEs depended on three parameters: f2 frequency, stimulation level and f2/f1 ratio. The results showed many differences between the characteristics of 2f1-f2 and 2f2-f1 DPOEs, probably due to their being generated by different mechanisms. Thus, the 2f2-f1 DPOEs may provide different information about the cochlear status and could be of clinical interest.

Acoustic Stimulation↗
PubMed1998

[Acute and chronic sphenoid sinusitis. Review of the literature].

Isolated involvement of the sphenoid sinus is a relatively uncommon entity. We present a review of the most important series. Acute and chronic diseases are separated. Acute sphenoid sinusitis is a potentially catastrophic infectious disease. It is frequently initially misdiagnosed, and, due to the severe intracranial complications, a genuine medical and surgical treatment is recommended. Chronic sphenoid lesions may pose a problem of etiologic diagnosis. It may be difficult to differentiate between benign and malignant lesions. The most common presenting symptom is headache, followed by visual symptoms and cranial nerves palsies. Radiographically, computed tomography is the gold standard. Treatment includes antibiotic therapy and surgical drainage. This drainage is now done through an endoscopic approach.

Acute Disease↗
PubMed1998

[Clinical, etiologic and therapeutic aspects of chronic sphenoid opacities].

A series of 23 patients with sphenoid disease were seen between 1992 and 1997. The most common symptom was headache. This headache was found to be nonspecific. Cranial nerve abnormalities were found in two patients. The different types of radiolographic images were analyzed, and compared with the surgical diagnosis. Twenty-one patients underwent surgical exploration by intranasal endoscopic sphenoidotomy. This approach allowed drainage and inspection of the sinus.

Adult↗
PubMed1997

A case report of fluctuant sensorineural hearing loss after hepatitis B vaccination.

Hepatitis B vaccine is known to induce accidents and side-effects. We report a case of unilateral fluctuant sensorineural hearing loss with tinnitus after a series of hepatitis B vaccinations. Tinnitus regressed and hearing thresholds were normalized 6 months later. The authors discuss the potential causality of hepatitis B vaccine in the occurrence of fluctuant sensorineural hearing loss and propose a physiopathological hypothesis to explain this unusual case.

Adult↗
PubMed1997

Statistical evaluation of hearing screening by distortion product otoacoustic emissions.

The aim of this study was to provide a statistical evaluation of the screening properties of distortion product otoacoustic emissions (DPOEs) in individuals with clinically normal hearing and in patients with pure sensorineural deafness of various degrees. The main informational parameters used were sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the analysis of receiver operating characteristic (ROC) curves. For each frequency tested, ears were classified as a function of their audiometric threshold. Two groups were defined relative to an arbitrary reference, the "audiometric criterion." The PPV decreased and NPV increased with increases in the audiometric criterion. Each point of the ROC curve represents the relationship between the false alarm rate and the hit rate for each audiometric criterion ranging between 10 and 75 dB hearing level: the lower the audiometric criterion, the lower the hit rate value, and the lower the false alarm value. The audiometric criterion giving the highest hit rate and the lowest false alarm rate was 55 to 60 dB hearing level for primaries at 60 and 70 dB sound pressure level, or 25 to 30 dB hearing level for primaries at 30, 40, and 50 dB sound pressure level. These two different behaviors of ROC curves are consistent with the hypothesis that DPOEs do not represent activity at a single location along the basilar membrane.

Adolescent↗
PubMed1996

[Characteristics of 2F2-F1 distorsion products in adults with normal hearing].

Acoustic distorsion products (ADP) are otoemissions which the cochlea emits in response to stimulation by two pure frequencies, f1 and f2. ADP 2f1-f2 has been widely studied, however little work has been reported on ADP 2f2-f1. We performed a study in 34 adults with normal hearing to determine the normal values (incidence and amplitude) of ADP and compared them with the ADP 2f1-f2. Two f2/f1 ratios were used (1.22 and 1.12). Different behaviors were observed between the two types of ADP. These results suggest that the mechanisms generating the two ADP are different and that, consequently, ADP 2f2-f1 should have clinical implications different than ADP 2f1-f2.

Acoustic Stimulation↗
PubMed1995

Transient-evoked otoacoustic emissions and high-frequency acoustic trauma in the guinea pig.

Transient-evoked otoacoustic emissions (TEOE) disappear when hearing loss exceeds 40 dB in the range 1-4 kHz, due to impairment of cochlear outer hair cells. Early screening of sensorineural hearing losses is based on this finding. However, little is known as to the frequency specificity of TEOE abnormalities in a damaged cochlea. TEOE were recorded in 18 normally hearing guinea pigs in a range from 1.5 to 5 kHz before and after exposure to loud pure tones (3-10 kHz, 95-105 dB SPL, 1-10 min). The thresholds of eighth-nerve compound action potentials (CAP) were monitored with a round-window electrode; it was confirmed that acoustic overexposure resulted in typical high-frequency threshold elevations (10 to 50 dB). Most TEOE components were found at lower frequencies at which CAP thresholds did not change. However, a significant linear regression was found between their amplitudes and the percentage of basal cochlea with unaltered CAP thresholds (r = 0.69, p < 0.0001). Two alternative hypotheses are proposed to account for this correlation. Either acoustic trauma induced some minute cochlear damage at places tuned to low frequencies and TEOE were more sensitive to it than CAP thresholds, or significant contributions to lower-frequency TEOE came from the most damaged cochlear places tuned to much higher frequencies.

Acoustic Stimulation↗
PubMed1994

Auditory threshold evaluation by distortion-product oto-acoustic emissions using decision support system.

Distortion-product oto-acoustic emissions (DPOEs) were measured in 102 normal-hearing and hearing-impaired ears to examine the sensibility, specificity, positive predictive value and negative predictive value of this test in a real clinical setting using two decision support systems. The first model only considered the presence or the absence of DPOEs in response to a 52 dB SPL stimulation intensity. The second model used two consecutive tests: i) the presence or the absence of DPOEs in response to a 52 dB SPL stimulation intensity, and ii) evaluation of the slope of each DPOE input-output function. The sensitivity of these two models varied between 1 and 0.83 whereas the specificity varied between 0.95 and 0.72 as a function of the frequency tested. The first model proved to be a very sensitive test, but the introduction of a second criterion of decision (i.e., the slope of DPOE input-output function) did not enhance the validity of the test.

Acoustic Stimulation↗
PubMed1994

[Role of the basal cochlea in the genesis of evoked acoustic oto-emissions in the subject with normal hearing].

The aim of this study was to determine the role of the basal part of the cochlea (8-16 kHz) on the genesis of evoked otoacoustic emissions (EOEs) in normally hearing subjects (0.25-8 kHz thresholds below or equal to 20 dBHL). This study was realized on 43 subjects. The EOEs were generated by a linear click of 0 dB (ILO88 Ref.). The high-frequency (8-16 kHz) audiometric thresholds varied between 30 and 74 dBHL while conventional audiometric thresholds were below 20 dBHL. Correlation studies between EOE amplitude and audiometric thresholds were statistically significant only when the high frequency thresholds were considered. Those data are a new argument for the hypothesis that EOEs are generated by the global cochlear activity.

Adult↗
PubMed1992

[Long-term esophageal and oropharyngeal pH-metry in ORL manifestations of gastroesophageal reflux in children].

Several studies published over the last few years have pointed out the importance of gastroesophageal reflux (GER) in the pathogenesis of certain cases of chronic or recurrent pharyngo-laryngitis. While the presence of an acid reflux at the level of the pharyngo-larynx has recently been demonstrated in certain cases, the real incidence and pathogenic impact of this reflux is not precisely known. A new technique of continuous 24 hour bi-level monitoring of endoluminal pH in the esophagus and the oro/hypopharynx has made it possible to observe the variations in acid-base balance in contact with the pathological mucosa. 21 patients, 2 months to 7.5 years old, presenting recurrent episodes of pharyngitis or laryngitis, underwent continuous pH monitoring during a 24 hour hospitalization. 6 control subjects, 1 month to 13 years old, presenting no chronic or recurrent ear, head or neck pathology and no sign or symptom of GER were subjected to the same monitoring regimen. A statistically significant difference between the 2 groups is evident for most of the parameters analysed. The most discriminative parameter is the fraction of the total recording time where the pharyngeal readings remain under ph6 (p < 0.0005). These results demonstrate that, in this clinical condition, acid of gastroesophageal origin is in contact with the pharyngeal mucosa. This suggests that the acid has a causal role in the pathological changes observed in the pharyngolaryngeal mucosa.

Child↗