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Biomedical subjects

M F Colman

Publications and source records attributed to M F Colman.

27 records · Page 2Linked to original sources

Kawasaki disease in adults. An otolaryngologist's perspective.

Kawasaki disease has been recognized for more than 15 years in children, but it is only recently that adult cases have been known to occur. One such case is reported herein. The cases of previously described adult patients are reviewed in depth, emphasizing the otolaryngologic findings. Diagnosis is based on clinical findings with prominent fever, oropharyngeal erythema, dermatitis, and cervical lymphadenopathy. The underlying lesion is a vasculitis and treatment is mainly supportive, although aspirin seems to have some value in the prevention of cardiac complications.

Adolescent↗

Odontogenic myxoma.

The odontogenic myxoma is a relatively rare benign tumor occurring in the jaws. When the lesion is large and when presenting in a difficult location, aggressive initial therapy affords the most successful outcome. Histologic, radiographic and behavioral characteristics of this rather persistent tumor are briefly reviewed and an approach to diagnosis and definitive treatment of a large maxillary odontogenic myxoma is presented.

Adolescent↗

Acute, life-threatening disease first appearing as odontogenic pain.

Rapidly spreading rhinocerebral infection by Phycomycetes (mucormycosis) in a diabetic patient with ketoacidosis is described. The dentist and dental specialists should be alert to the early signs and symptoms of this disease as they evaluate and follow patients who are debilitated and who have odontogenic pain. It cannot be overemphasized that a successful outcome is critically dependent on early recognition and prompt therapy, especially in a person with diabetic acidosis as death may occur within 2-5 days after the first symptoms appear.

Acute Disease↗

Gunshot wound to the mandible with secondary neck injuries.

Four consecutive patients were initially seen with witnessed, low-velocity gunshot wounds to the mandible with deflection of the bullet into the neck, causing a life-threatening situation. The mechanics of injury were similar in all four patients who were shot at close range with a moderately heavy caliber handgun and sustained comminuted fractures from the parasymphyseal area to the ascending ramus of the jaw. Severe vascular injuries were seen in three cases and lacerations of the pharynx and cervical esophagus in one. Aggressive management of these injuries is recommended, with neck exploration after endoscopy playing a major role. Management of the mandibular fracture at the time of the initial surgery is favored. However, if roentgenograms are unavailable, reduction and fixation may need to be deferred.

Adult↗

Deep neck abscesses secondary to methylphenidate (Ritalin) abuse.

Methylphenidate (Ritalin) abuse has been and continues to be a major medical and social problem. In the past 6 months, we have seen five deep neck abscesses secondary to intravenous Ritalin abuse. This constitutes more than 50% of the deep neck abscesses seen by us in the same time period. The pathogenesis is related to an inflammatory foreign-body reaction to the fillers in the methylphenidate tablets, followed by superinfection by oral or cutaneous flora. Mixed flora infections with weakly pathogenic organisms may also occur.

Abscess↗

A dramatic complication of peroral fiberoptic endoscopy.

The advent of the flexible fiberoptic gastroscope has revolutionized clinical gastroenterology. The morbidity and mortality rates with flexible fiberoptic endoscopes are comparable to those associated with rigid and semirigid scopes. Insufflation devices are routinely used with flexible fiberoptic scopes. This may lead to complications, differing from those associated with rigid endoscopy. A case involving an insufflation injury to the piriform sinus is presented. The pathophysiology of insufflation injuries and their management are discussed.

Air↗

Epiglottitis in immunocompromised patients.

Modern medical oncology has made dramatic improvements in the prognosis of many malignancies. Many of the treatment regimens used by the chemotherapist have the potential to profoundly depress the immune system. At UCLA Medical Center, three patients developed epiglottitis secondary to the fungus Candida albicans, while profoundly immunocompromised. All three had severe pain and odynophagia. The patients were all managed medically and none went on to airway obstruction. The natural history of this process is reviewed.

Adult↗