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Biomedical subjects

M F Glickstein

Publications and source records attributed to M F Glickstein.

17 recordsLinked to original sources

Traumatic intramyocardial dissection secondary to significant blunt chest trauma: a case report.

The case of a patient with delayed mitral regurgitation and right coronary artery traumatic injury in association with intramyocardial dissection without rupture or pseudoaneurysm is presented. These findings evolved secondary to blunt chest trauma and were confirmed by cardiac ultrasound scanning, magnetic resonance imaging, and cardiac catheterization. Successful surgical correction was facilitated with this combination of diagnostic testing.

Adult↗

Time-dependent scar enhancement in magnetic resonance imaging of the postoperative lumbar spine.

Magnetic resonance imaging (MRI) has become a principal modality in the evaluation of the post-operative lumbar spine. Gadolinium-diethylenetriamine-pentaacetic acid (Gd-DTPA) can often facilitate differentiation of scar from recurrent disc herniation according to established criteria. Scar has been believed to enhance predictably. We reviewed the contrast-enhanced MR scans of 44 patients who were examined for recurrent back pain following disc surgery and attempted to assess the enhancement characteristics of scar as a function of the time interval between initial surgery and the imaging study. In 44 patients, scar was believed to be present at 32 of 49 disc levels. The degree of enhancement was related to the postoperative interval; those studies performed no later than 9 months after surgery tended to exhibit the greatest degree of enhancement. Surgical confirmation of these MRI findings was available in 12 patients. In patients examined long after surgery, scar enhancement may be less intense than in those examined shortly after surgery, or even nonexistent. This temporal factor should be considered when using contrast material to differentiate scar from recurrent disc herniation in post-operative examinations of the lumbar spine.

Adult↗

Cross-sectional imaging of idiopathic solitary renal vein varix: report of two cases.

Two cases of solitary renal vein varices are reported which presented as incidental findings on abdominal computed tomography (CT) and were initially thought to represent retroperitoneal lymph nodes. Contrast-enhanced CT, magnetic resonance imaging (MRI), and Doppler ultrasound (US), all demonstrated the vascular nature of these masses suggesting the correct diagnosis. When a rounded soft tissue density mass is seen on noncontrast-enhanced CT either in or contiguous to the renal hilum, a renal vein varix must be excluded. Doppler US, MRI, or dynamic contrast-enhanced CT should be done to exclude a renal varix as the cause.

Aged↗

Hypointense renal cell carcinoma: MR imaging with pathologic correlation.

In two pathologically documented cases of renal cell carcinoma, the appearance of the tumors at magnetic resonance (MR) imaging was markedly hypointense relative to normal renal parenchyma on both T1- and T2-weighted spin-echo images. Pathologic examination of both tumors revealed diffuse iron scattered throughout the tumors. The paramagnetic effect of the iron may account for this unusual hypointense appearance at spin-echo imaging, independent of pulse sequence.

Carcinoma, Renal Cell↗

Optimizing heparin utilization in angiographic flush solutions.

Various concentrations of heparin in angiographic flush solutions are employed during angiography. In an effort to determine whether differences in outcome are seen when either high or low concentrations of heparin in angiographic flush solutions are utilized, two groups of patients were evaluated. There was no difference in outcome and a small systemic effect from heparin was seen in both groups. Use of a low concentration of heparin is suggested for routine angiography.

Angiography↗

CT anatomy of the internal mammary vessels: importance in planning percutaneous transthoracic procedures.

Knowledge of the anatomy of the internal mammary vessels is important to avoid hemorrhagic complications when an anterior parasternal approach is used for percutaneous transthoracic procedures such as biopsy and empyema drainage. We examined 100 consecutive CT scans of the thorax to assess both the number of internal mammary vessels and their relation to the sternum. The mean distance from the sternum to the most medial vessel, the internal mammary vein, was 1.03 +/- 0.25 cm on the right side and 0.98 +/- 0.23 cm on the left side. The mean distance from the sternum to the most lateral vessel, the internal mammary artery, was 1.57 +/- 0.30 cm on the right and 1.47 +/- 0.30 cm on the left. Three internal mammary vessels were present in 20% of cases on the right side and in 18% on the left side. In nine patients, the internal mammary artery was greater than 2.0 cm from the lateral border of the sternum. We recommend an approach that is greater than 2.5 cm from the sternal border when performing parasternal percutaneous transthoracic procedures in order to avoid hemorrhagic complications from injury to the internal mammary vessels. A "safe" window does exist medially between the sternal border and the internal mammary vein but should be used only in procedures performed under CT guidance.

Adolescent↗

Magnetic resonance demonstration of hyperintense herniated discs and extruded disc fragments.

Magnetic resonance (MR) imaging is useful in evaluating a variety of spinal pathologies including intervertebral disc disease. Herniated discs are commonly believed to undergo premature degeneration and produce low intensity signal on T2-weighted images. We reviewed 154 patients who were studied for disc herniations or other pathology. Fifty-nine (38%) had disc herniations and 7 of these (5%) had a fragment that was hyperintense with respect to the adjacent intervertebral disc on T2-weighted images. It is hypothesized that some disc fragments may contain a higher water content that causes prolongation of the T2 signal. The bright signal which is therefore seen on long TR long TE (T2-weighted) images may be a useful sign suggesting herniation or extrusion.

Adult↗

Pulmonary lymphoproliferative disorders.

Nonlymphomatous pulmonary lymphoproliferative disorders include plasma cell granuloma, Castleman's disease, pseudolymphoma, lymphocytic interstitial pneumonitis, angioimmunoblastic lymphadenopathy, and lymphomatoid granulomatosis. They are thought to represent a hyperplasia of the pulmonary immune system in response to chronic antigenic stimulation. A description of the variable clinical, radiographic, and pathologic features of each entity is presented.

Humans↗

Avascular necrosis versus other diseases of the hip: sensitivity of MR imaging.

Magnetic resonance (MR) imaging of the hip has been useful in the examination of patients for the presence of avascular necrosis (AVN). In the detection of AVN, MR imaging is more sensitive than computed tomography or nuclear scintigraphy. This study assessed the usefulness of MR imaging in the differentiation of AVN from other hip diseases. Twenty-two cases of non-AVN hip disease were matched with 23 biopsy-proved cases of AVN and ten normal controls. MR images were rated in a blinded manner by five experienced radiologists, and receiver operating characteristic (ROC) analysis was performed on the data. In the discrimination of AVN from other hip diseases or from normality, the A(z) value (the area under the ROC curve) was 98.6. With a specificity of 98%, MR imaging was 97% sensitive in the differentiation of AVN from normality, 85% sensitive in the differentiation of AVN from non-AVN disease, and 91% sensitive in the differentiation of AVN from both conditions. MR imaging may therefore help discriminate between AVN and other hip diseases.

Diagnosis, Differential↗

Pulmonary sarcoidosis in the older patient: conventional radiographic features.

The clinical and radiographic findings in 29 patients presenting with pulmonary sarcoidosis after the age of 50 years were reviewed. Fifty-nine percent (17 patients) had atypical findings at presentation. The atypical patterns at radiography included mediastinal adenopathy alone or in combination with unilateral hilar adenopathy (n = 8), solitary or multiple pulmonary masses (n = 3), and atelectasis (n = 3). Five patients had extrathoracic tumors at the time that the diagnosis of pulmonary sarcoidosis was made, which confused the diagnosis at radiography. An enhanced awareness of the atypical patterns of sarcoidosis in the older patient may facilitate the diagnostic process.

Age Factors↗

Paraspinal lipomatosis: a benign mass.

Paraspinal lipomatosis usually occurs in patients with steroid excess. In two patients a paraspinal mass was detected on conventional radiographs and was subsequently shown to represent benign fat deposition on computed tomography, thereby obviating further studies. Neither patient had been receiving steroids. Paraspinal lipomatosis may be the cause of a benign mass and may be considered in the differential diagnosis of this finding.

Aged↗

Mesenteric panniculitis: findings on CT, MRI, and angiography. Case report.

The computed tomography (CT), magnetic resonance (MR), and angiographic features of a case of mesenteric panniculitis are presented. The MR characteristics of this rare disorder have not previously been reported. The value of MR in arriving at the preoperative diagnosis of this disorder is discussed.

Aged↗