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Biomedical subjects

M F Jancloes

Publications and source records attributed to M F Jancloes.

5 recordsLinked to original sources

Selected economic issues in helminth control.

This paper examines four main economic issues in the formulation of helminth control policies: whether, what, how and with whose resources to control helminthiasis. The paper argues that (i) although helminth control would have a negligible impact on mortality, its nutrition-mediated effects on improved labor productivity and intellectual performance may be significant; (ii) that reduction of helminth disease rather than infection should be the target of control policy, although the preferred intervention may still be eradication rather than continuous control; and (iii) that although the case for public subsidy of helminth control interventions is strong, the existence of serious fiscal constraints and some evidence of private willingness-to-pay for anthelminthic chemotherapy indicates a potential for partial cost recovery which should be explored.

Communicable Disease Control↗

[Epidemiological control of intestinal nematodoses in a rural area of Zaïre (author's transl)].

In order to establish the rational organization of a mass campaign intended to control intestinal parasites in villages of a rural zone in Lower Zaïre, a prevalence study was made of a total population of 3,056 inhabitants. Coprologic examination allowed to determine the following mean levels of prevalence: Ascaris, Lumbricoides 57 per cent, ankylostoma 51 per cent, Stronglyoides stercoralis 14 per cent and Trichuris trichiura 11 per cent. In a prospective survey of nine months allowed to determine the optimal therapeutic coverage to be realized in the municipalities concerned using the epidemiological date as a reference.

Adolescent↗

Mass control of ascariasis with single oral doses of levamisole. A controlled comparison in 3,056 subjects between three incomplete population coverages.

Ninety-, 60-, and 40-percent population coverages with levamisole 2.5 mg/kg of body weight were compared for their effects on Ascaris lumbricoides, ancylostoma, Strongyloides stercoralis, and Trichuris trichiura infections. They were shown to be effective in maintaining a reduced prevalence of A. lumbricoides in the treated subjects for 9, 6, and 3 months, respectively. Nine months after treatment, the prevalence of ascariasis was still lower than before treatment both in the levamisole and in the control subjects, regardless of the population coverage. This was probably because the egg output had been reduced. It is concluded that mass treatment with single oral doses of levamisole repeated at 3-month intervals might help control ascariasis, and that population coverages between 60 and 90% might be appropriate. No clear-cut effects against hookworms could be shown, possibly because the first follow-up examinations were performed three months after treatment. No changes in the prevalence of S. stercoralis and T. trichiura could be demonstrated. There were no adverse exp

Administration, Oral↗