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Biomedical subjects

M F Smolin

Publications and source records attributed to M F Smolin.

4 recordsLinked to original sources

Digital subtraction ductography.

Digital subtraction techniques used in the examination of eight patients with salivary and nasolacrimal disease are described. Pleomorphic adenoma, ductal stricture, extrinsic masses, parotid-otic fistula, and a radiolucent calculus were demonstrated. The procedures are more easily performed than film techniques, and pathology is better demonstrated by digital ductography than on a film examination. Image subtraction, reregistration, and window manipulation allowed clear demonstration of ducts about the head and neck, overcoming limitations imposed by inherently high object contrast. Digital subtraction ductography is an important nonvascular application of digital imaging technology.

Adult↗

Digital tomography: description and preliminary clinical experience.

Digital tomography was performed in 30 patients using a new prototype system with a PET-Scope image tube. Twenty-eight exposures are obtained during a single revolution of the x-ray source over the volume of tissue to be imaged. The sum of the radiation produced by the 28 exposures is about equivalent to a single routine exposure of the part imaged. The data accumulated can provide up to 200 tomographic sections at intervals of 5 mm. Reconstruction time for each section is 3 sec. The raw images may be reconstructed as often as desired. Algorithms are being developed to allow axial and sagittal reformations. Further work is required to improve spatial resolution and contrast and to develop algorithms to allow subtraction of blurred images above and below the reconstructed site. The authors believe that digital tomography may eventually replace most routine tomograms.

Adult↗

Treatment of tandem lesions of the extracranial carotid artery.

The authors present a patient with bihemispheric transient ischemic attacks attributed to stenosis of the left common carotid origin and stenosis and ulceration of the left cervical internal carotid artery. Because of precarious cerebral blood supply secondary to occlusions of the right common carotid and left vertebral arteries, several measures were undertaken perioperatively to provide protection from cerebral ischemia during vessel occlusion. These included Swan-Ganz catheter monitoring to maximize cardiac output and maintain satisfactory hydration, normocarbia, satisfactory oxygenation, and moderate hypertension and barbiturate infusion. With these adjuncts, both lesions were treated together. Retrograde balloon angioplasty under fluoroscopic control of a significant stenosis of the common carotid artery origin was performed before carotid endarterectomy. Postoperative digital subtraction angiography demonstrated a satisfactory technical result. The management of tandem lesions of the extracranial carotid artery is discussed. Balloon angioplasty coupled with extracranial vascular reconstructive procedures may allow the management of lesions not treated safely or effectively by either technique alone.

Angioplasty, Balloon↗

Angiographic nephrectomy using iodinated contrast agent.

Diatrizoate meglumine and sodium (Renografin-76) was perfused in an obstructed renal artery in 13 dogs. Intense and prolonged accumulation of contrast agent ("contrast staining") was achieved in all animals. Repeat injection was frequently necessary to enhance staining. Renin output from the stained kidneys was lower than that from the opposite kidneys. Angiography at 14-18 weeks demonstrated a marked decrease in renal size in all dogs, with complete occlusion of the renal artery in two dogs. No collateral circulation was discerned. Grossly, all experimental kidneys were uniformly shrunken. Histologically, diffuse renal infarction was evident with coagulative necrosis. Contrast staining is an effective method for uniform destruction of renal tissue.

Animals↗