[Embolization of the renal arteries in the treatment of kidney tumors].
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Biomedical subjects
Publications and source records attributed to M F Trapeznikova.
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The paper reviews the experience of the urological clinic in the treatment of 106 children with urolithiasis. The necessity of careful pretreatment examination to reject associated anomaly of the upper urinary tracts as a cause of lithogenesis is emphasized. Surgical treatment and extracorporeal lithotripsy which has proved highly effective against uroliths in children are considered.
656 urine and 78 blood samples were examined immunomicrobiologically. No bacterial growth was recorded in 43.8% of urine samples. Opportunistic bacteria were represented by Enterobacteriaceae, nonfermenting gram-negative bacteria with predominance of E. coli, P. mirabilis, P. aeruginosa isolated both in monocultures and in associations in conventional diagnostic titers (1g 5 CFU/ml). Throughout 40 days of the hospital stay microflora continuously changed, but until the discharge the infection persisted. The study of the immunological aspect of anti-infection resistance showed that most of the examinees (73%) at admission with pyelonephritis exacerbation have deficient cellular and humoral defense.
Potentialities of ultrasonic investigation (USI) in diagnosis of vesicoureteral reflux (VUR) were elucidated by comparison of the USI evidence with that obtained at miction cystourethrography which had identified VUR of degree I-IV. Ultrasonic signs of active and passive VUR distinctly observable in the reflux degree III and IV are noted. The technique of USI in VUR-suspected children is described. Ultrasonic measurements of the intravesicular part of the lower ureter were made. It is shown that USI can serve a method of outpatient selection for miction cystourethrography. As demonstrated by the examination of 58 patients with transplanted kidney, USI is effective in identification of the reflux to the transplanted kidney as well as in differential diagnosis with obstructive complications after transplantation.
The paper reports 3 cases of positive results achieved at extracorporeal lithotripsy for concrements in the transplanted kidney. To avoid such potential complications as subcapsular hematoma, rupture of the transplant, its ureter occlusion by the stone fragments, acute pyelonephritis, lithotripsy should be conducted in sparing regimen (low and moderate power, number of impulse per a session not more than 2000) under ultrasound control. In defective urine outflow from the transplant as a result of pretreatment obstruction by the stone or posttreatment obstruction by its fragments a drainage must be done by means of transcutaneous puncture nephrostomy.
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Ureteral strictures in kidney recipients are serious urological complications often responsible for the transplant rejection and sometimes for the recipient's death. The stricture-related slight and nonspecific symptoms often underlie its late diagnosis and inadequate treatment. Obligatory follow-up ultrasonic investigations promote early detection of ureteral stenosis. Eight kidney recipients with ureteral stricture initially underwent transcutaneous puncture nephrostomy preserving the transplant function and preventing aggravation of the condition. In view of threatening infection and weak reparative capacity of immunosuppressed patients, less traumatic transcutaneous interventions seem preferable in further treatment: bouginage, balloon dilatation or the stricture dissection followed by insertion of the inner stent. In uneffective transcutaneous surgery due to extended ureteral strictures or complete obstruction of the ureter it is valid to conduct pyeloureterostomy with the recipient's own ureter.
Therapeutic results of remote lithotripsy have been analyzed for 1016 patients with urolithiasis. The authors also focus on specific features of remote lithotripsy in anomalous stones, in nephroliths on the single and transplanted kidney, in location of the stone in the ureter. The efficacy of the procedure is reviewed in pediatric patients. Satisfactory results were achieved in 962 patients (95%). Remote lithotripsy is considered to be a valuable component of combined treatment of urolithiasis replacing successfully open surgery in 95% of the cases.
17 exacerbation and 13 latent CBP cases received ciprofloxacin in a dose 500 mg twice a day orally for 6-34 days. At pretreatment microbiological investigation of the prostatic juice 49 cultures of 7 microorganism species were isolated (12 cases of monoculture, 18 cases of 2-component associations). S. epidermidis and E. faecalis occurred more frequently (in 29.4 and 25%, respectively). Ciprofloxacin was highly active against all the isolated agents and by the number of sensitive to it strains proved superior to control antimicrobial drugs. Good and satisfactory treatment outcomes were achieved in 76.8% of patients. Side effects recorded in 8 patients (26.6%) caused the drug undue discontinuation in 1 patient only.
The material gained in the urological clinic of the Moscow Regional Research Clinical Institute covers 2000 cases of uroliths treated with extracorporeal lithotripsy (ECL) for 4 years. Factors implicated in the treatment outcomes, measures to prevent ECL complications, recommendations for ECL regimens in different clinical forms are specified.
Causes and mechanisms underlying nephrolithiasis after transplantation of the kidney differ much from known in other urological patients. We have found calculi in transplanted kidney in 5 of 939 surgical patients. Two cases of concrement formation in the transplant in the members of the same family aged 22 and 26 years we report as interesting. Our experience and literature data suggested family nature of the concrements. One of the patients underwent pyelolithotomy, the other impulse lithotripsy. Both the transplants function normally 5 years after kidney transplantation.
The paper presents the International system of overall score estimation of symptoms and life quality for patients with benign prostatic hyperplasia and reviews the results of this system application for objective diagnosis and evaluation of the efficacy of the treatment (chemotherapy, transurethral resection, transvesicular adenomectomy, transrectal hyperthermia, YAG-Nd laser prostatectomy) in 250 patients with benign prostatic hyperplasia. The fault of the system is the absence of specific recommendations for rating objective test results. The authors propose their variant of estimation of prostatic volume, maximal urination rate, residual urine.
Renal carcinoma and urolithiasis combine rather rarely. Postnephrectomy patients often consult the urologist when the condition is serious because of complications resultant from uroliths in the contralateral kedney. In view of solitary kidney, progressive chronic pyelonephritis, associated chronic renal failure surgical treatment of the condition becomes risky and necessitates individual approach to choice of therapeutic policy and definition of indications to urolithiasis treatment in patients after nephrectomy for renal carcinoma. This includes the decision whether to perform nephrolithiasis before or after nephrectomy and whether to attempt any surgery in the absence of urolithiasis clinical symptoms.
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