[Guidelines for the diagnosis and treatment of erectile disorders. NVIO (Dutch Society for Impotence Research) and NVU (Dutch Society for Urology)].
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Biomedical subjects
Publications and source records attributed to M F van Driel.
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OBJECTIVE: To determine indications and results of endourological upper urinary tract drainage in patients with obstruction due to malignancy. DESIGN: Retrospective. SETTING: University Hospital Groningen. METHOD: In the period 1987-1992, 57 patients with upper urinary tract obstruction due to cancer were treated primarily with a double-J stent (n = 21) or a percutaneous nephrostomy (n = 36, later replaced by a double-J stent in 13). RESULTS: Indications were: severe renal failure following bilateral ureteral obstruction due to malignancy (n = 17), or unknown cause (n = 19), to optimise a compromised kidney function before chemotherapy (n = 7), to resolve pain caused by unilateral obstruction (n = 10), or other (n = 4). The tumours originated most often in the cervix uteri, followed by the urinary bladder, the prostate and the corpus uteri. Minor complications occurred in 34 of the 57 patients (60%): transient haematuria (22 x), urgency caused by the distal tip of the double-J catheter (8 x), dislocation (17 x) or obstruction (6 x) of the nephrostomy catheter. Major complications were observed in 5 patients with a double-J stent: sepsis (1 x), catheter break (1 x), ureteral perforation (2 x) and fistulization between the ureter and iliac artery (1 x). Survival after drainage varied from several days to 8 years (mean 23 months). In 5 patients treated with drainage only to prolong survival, survival was 0.5-16 months (mean 7.3). CONCLUSION: Endourological drainage may be applied to patients with localised disease, in whom further therapy holds the promise of prolonged survival. However, in view of the low complication rate, selected patients who are on a palliative course and still have rapidly progressive disease can also benefit from extended life-time after endourological drainage.
Impotence is not only a problem of modern society. Centuries ago man has sought for causes and remedies for impotence, originally looking much more outside himself rather than within himself. This article reviews and reflects on mythological, religious and cultural aspects of impotence, especially before the beginning of the 18th century.
In a 13-year-old boy echographic investigation of the scrotum was carried out because spermatocele was suspected. On the right side an extra testicle was observed. Polyorchism is a rare anomaly with, as far as we know, 74 cases reported in the literature. It may result from transverse splitting of the urogenital ridge in the 4th till the 6th week of the embryonal phase. The accompanying disorders include inguinal hernia, cryptorchism and torsion. Malignancy in the extra testicle has been reported in 4 cases only. In the absence of any accompanying disorder and if testicular tumor can be ruled out by ultrasonography, there is no need for surgical exploration.
A computer-based search for literature on female sexual functioning after radical cystectomy and rectal cancer surgery revealed 11 articles. Although some prognostic variables are presented in the literature (age, the magnitude of surgery, hand-made vs stapled anastomoses, nerve content in the surgical specimen) there are very few definitive answers to the questions regarding which internal and external causal factors elicit and control sexual functioning after radical pelvic surgery. The review is concluded by some guidelines to help patients and their partners cope with sexual problems.
A patient was referred to our hospital for resection of a large renal cell carcinoma with invasion of the inferior caval vein, diagnosed as such with CT, angiography and cavography. The history mentioned partial resection of the left lung for lung carcinoma 16 months before. At operation the tumor could not be removed, the patient died because of postoperative pulmonary complications. Autopsy and histopathological examination revealed a large metastatic tumor of the previous lung carcinoma in the left adrenal gland. The clinical implications and some diagnostic methods are discussed.
We report on a patient with an ureteroiliac artery fistula, which developed after double J stenting. The stent was introduced because of unilateral hydronephrosis 2 months after a Wertheim-Meigs operation preceded by cesium application. The presenting symptom of gross hematuria was initially misjudged to originate from the kidney. The diagnostic difficulties in this case are discussed.
Intracavernous papaverine injection has gained widespread acceptance in the treatment of erectile impotence. The opposite problem--priapism--can be treated with the same technique using a vasoconstrictive drug such as adrenaline. We report on eight patients successfully treated for priapism by intracavernous injection of adrenaline.
Intracavernous papaverine injection therapy has gained widespread acceptance in the treatment of erectile impotence. Treatment for the opposite, priapism, is also possible with the same technique using a vasoconstrictive drug. We report 5 patients with priapism successfully managed by intracavernous injection with adrenalin.
Intracorporeal papaverine self-injection therapy has gained widespread acceptance in the treatment of impotence. Treatment for the opposite, recurrent priapism, is also possible with the same technique using a vasoconstrictive drug. We report a patient with idiopathic recurrent priapism successfully managed by intracorporeal self-injection with epinephrine.
Severe, massive bladder haemorrhage is a difficult and often frustrating clinical problem. The aetiologies are numerous and include irradiation, malignancy, severe infection and drug-induced changes. Among the numerous modalities of treatment that have been reported formalin, phenol and silver nitrate instillations have often been associated with significant side effects, morbidity and mortality and have had varying degrees of success. During the last two years we have used continuous closed irrigation of a sterile 0.5% alum solution in 16 patients. Alum is an astringent and acts by protein precipitation over the bleeding surface. Because of a low cell permeability its action is limited to the cell surface and interstitial spaces. The permeability of the cell membrane is reduced but remains viable. The preparation and the pharmaceutical aspects of the 0.5% alum irrigation will be discussed. The conclusion is that the technique of managing massive bladder haemorrhage is simple, efficient, nontoxic and less expensive than previously reported therapies. Therefore, irrigation with alum before instituting invasive means to control bleeding is recommended.
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Five cases of juvenile polyps at the level of a ureterosigmoidostomy are described. One of the juvenile polyps contained an area of adenomatous tissue. The mechanisms that might cause these polyps are discussed. The mechanisms that might cause these polyps are discussed. The presence of adenomatous tissue in one of the patients may be a step of the polyp cancer sequence at the level of ureteral implantation in the colon. The authors make a plea for a call-up and close follow-up of all patients who have a ureterosigmoidostomy.
Radionuclide renography showed an obstructed pattern in 6 patients with meningomyelocele without dilatation of the upper urinary tract or reflux when the bladder was filled to the volume that during previous urodynamic testing had resulted in an intravesical pressure of 40 cm. water but not when these patients were studied with an empty bladder. Therefore, this study indicates that treatment should be directed at avoiding long-standing intravesical pressure exceeding 40 cm. water in patients with meningomyelocele.
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