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Biomedical subjects

M Fauchet

Publications and source records attributed to M Fauchet.

16 recordsLinked to original sources
PubMed1978

[Medical applications of cyclotrons (author's transl)].

Isochronous cyclotrons used to accelerate different charge particles (protons, deuterons, alphas...) at variable energies, have important medical applications, for neutron teletherapy, in vivo or in vitro activation analysis or production of short-lived radioisotopes for nuclear medicine. The characteristics of the cyclotron presently available are described for these three applications (low energy "compact" cyclotrons, cyclotrons of intermediate and high energies), and their advantages are discussed from the points of view of the medical requirements, the financial investments and the results obtained.

Activation Analysis↗
PubMed1977

[Study of the coronary arteriole bed at rest and during hyperemia by selective coronary scintigraphy with labeled microspheres].

The hyperemic response induced by the tri-iodinated contrast agent injection for coronarography assesses functional value of the arteriolar areas of coronary distribution. The intracoronary injection of two kinds of micropheres labeled with gamma emitter radionuclides of different levels of energy (99m-Technetium and 113m-Indium) provides comparison of the studied areas-scintigraphies at rest and during hyperemia.

Arterioles↗
PubMed1977

[Value of hemodynamic surveillance by radiocardiography in human heart transplants].

Eighteen cases of cardiac transplantation have been carried out for 16 recipients since October 1973, there being 8 survivors at present. The importance of screening in such a treatment is vital. It is a simple method, easy to control, can be carried out at the bedside, is reproducible, reliable, and completely harmless, and by allowing the haemodynamic function of the graft to be seen at all times, helps in the marching of the donor and the recipient, in following the function of the graft in the immediate post-operative period, and in discovering rejection crises, and evaluating the long-term fate of the transplant.

Adult↗
PubMed1976

[Quantitation of mitral and aortic regurgitation using the effective systemic ejection fraction measured by radiocardiography and scintography of the cardiac cavities].

Comparison between the effective systemic ejection fraction defined by radiocardiography and cardiac chambers scanning, and the whole left ventricular ejection fraction calculated by cineangiocardiography allows an accurate assessment of mitral and aortic regurgitation extent. In case of both mitral and aortic insufficiency, each regurgitation can be quantitatively dissociated by means of the aortic isotopic dilution curve recorded at the same time as the radiocardiogram.

Aortic Valve Insufficiency↗
PubMed1976

[Selective coronary scintigraphy using labelled microspheres].

Selective intracoronary injection of microspheres labelled with radioactive substances which emit gamma rays with different energy levels (Indium 113 m and Technetium 99 m) allows us to explore by scintigraphic methods the areas of distribution of the two coronary arteries. Having been carefully calibrated, the particles are injected in limited numbers, and block the precapillary arterioles, where they gradually diminish in number. Scintigraphic examination is carried out in various projections (anteroposterior, left anterior oblique and right anterior oblique) immediately after coronary arteriography. Coronary scintigraphy allows us to establish the integrity of the distribution network of a coronary trunk which appears normal on coronary arteriography, to visualise the diminution of flow caused by a stenosed but patent trunk, and to visualise the extent of the collateral circulation and the quality of revascularisation achieved by an aorto-coronary bypass operation.

Angina Pectoris↗
PubMed1976

[Radioisotope measurement of left ventricular ejection fraction. Comparison with results of cineangiocardiography].

The combination of radiocardiography with scintigraphy of the cavities of the heart allows us to calculate the effective systemic ejection fraction. The systolic volume effectively ejected into the systemic circulation is obtained from radiocardiography using Stewart-Hamilton's principle. It is correlated with the left ventricular end-diastolic volume as calculated by planimetry on the scintigraphic record of the cavities of the heart, making due allowance for the geometrical axis of the heart. The ejection fraction measured by this isotope method has been compared with the ejection fraction measured by selective left ventricular cineangiography, both measurements being carried out at an interval of less than 48 hours in 100 patients without valvular disease. The results show an excellent correlation between the two methods (r = 0.94). In the 15 cases where the haemodynamic status of the ventricule appeared to be normal, the ejection fraction meastured by the two techniques was 0.65 +/- 0.04 and 0.66 +/- 0.04 respectively. In those patients with valve disorders with incompetence, the effective systemic ejection fraction is always lower than the total ejection fraction given by cineangiography. The difference corresponds with the fraction of the blood volume which is regurgitated.

Angiocardiography↗
PubMed1975

[A dynamic study of myocardial perfusion using radioisotope analysis of coronary blood flow during auricular stimulation].

Reproductibility of the radiocardiographic method using 42 Potassium has been verified. Coronary blood flow has so been measured in 50 control subjects and coronary heart disease patients, at steady state and during auricular pacing at 150 beats per minute. In control subjects group, under auricular packing coronary blood flow increases by a mean value of 15%; on the other hand it decreases by a mean value of 32% in coronary heart disease patients bearing obvious coronarography lesions. The cardiac output coronary fraction increases by a mean value of 27% in the control subjects group; it remains unchanged in coronary heart disease patients. On the contrary this coronary fraction increases in a significant way after functional aortocoronary bypass.

Adult↗
PubMed1975

[Measurement of mean pulmonary pressures and right systolic ventricular pressure by radiocardiography].

Computer exploitation of some parameters of the radiocardiogram and of the pressures measured by catheterization in a series of 678 subjects, studied both in Paris and in Prague, has made it possible to establish regression equations providing the rates of mean pulmonary arterial and wedge pressures together with the systolic right ventricular pressure on the basis of the radiocardiogram data. The latter was obtained by the conventional technique of the isotope dilution curves or by gamma-angiocardiography. Easy repetition of radiocardiography makes it an interesting investigation for the haemodynamic follow-up of the patients with heart disease.

Barium↗
PubMed1975

[Criteria of detection and treatment of rejection crises following human cardiac transplantation in a series of 10 cases].

Analysis of a series of 10 cardiac transplantations confirmed that the reject phenomena have a paroxysmal course, the diagnosis of which is different according to the time occurence of the reject crises, whether early (acute early rejection) or late (late acute rejection or chronic rejection). Because of the early diagnosis based on the follow-up of the electrocardiogram, of coagulation, of the graft flow, overcome eight rejection crises on the 3 patients with middle-term survival.

Adrenal Cortex Hormones↗
PubMed1975

[Radioisotope measurement of coronary flow with atrial stimulation in the normal subject and in patients with coronary disease].

The induction of atrial systole by stimulation is a means of demonstrating insufficiency of myocardial perfusion, even where there is a normal coronary flow under basal conditions in a genuine case of coronary atherosclerosis. The method, which entailed the use of radiocardiography with potassium 42, was first checked for reproducibility. The coronary flow was then measured under basal conditions, and subsequently during or after atrial stimulation at 150/min. in a group of 50 controls and coronary patients. Under atrial stimulation, the value increases by an average of 15 per cent in the controls, and decreases by an average of 32 per cent in cardiac patients with vessels which are patent on coronary angiography. The coronary moiety of the cardiac output increases by an average of 27 per cent in the controls, but does not change significantly in the coronary group. After aorto-coronary by-pass, the coronary moiety of the cardiac output is increased significantly during stimulation when the by-pass is patent.

Adult↗