Biomedical subjects
M Fischer-Williams
Publications and source records attributed to M Fischer-Williams.
Partial and generalized seizures associated with cerebral ischemia.
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Treatment of low back strain with electromyographic biofeedback and relaxation training.
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Recent advances in the study of cerebrospinal fluid.
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Cerebrospinal fluid proteins and serum immunoglobulins. Occurrence in multiple sclerosis and other neurological diseases: comparative measurement of gamma-globulin and the IgG class.
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Pathogenesis of seizures recorded in a general hospital.
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Transient cortical blindness. An unusual complication of coronary angiography.
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Light-induced epilepsy in the baboon, Papio papio: cortical and depth recordings.
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Comparison of evoked responses to click from different areas of the scalp in monkey, and from the scalp as compared with the cortex.
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[Photosensitive epilepsy in the baboon Papio papio: clinical and electroencephalographic (cortex and deep structures) study].
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A new multipurpose brain depth probe: long-term implantation and electroencephalographic recording in man, monkey, and cat.
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A family study of the biochemical defects in Wilson's disease.
Estimations of serum copper, serum ceruloplasmin (immunochemical), and urinary amino-acids excretion (quantitative and chromatographic) in 44 healthy relatives of patients with Wilson's disease (39 from one family) are reported. Each technique revealed some abnormal individuals. Good agreement was obtained between the serum copper and serum ceruloplasmin estimations and between the quantitative and chromatographic estimations of amino-acid excretion. Some individuals were abnormal to one or other of the pairs of tests only. These results cast doubt on the hypothesis that the symptoms of Wilson's disease are secondary to a quantitative (or qualitative) abnormality of ceruloplasmin. They also suggest that the mode of inheritance of the biochemical defects may be more complicated than that of a simple recessive mutant gene. Two of the relatives (one pregnant and one immediately post-partum) had a high serum copper level, as is expected in pregnancy, but normal serum ceruloplasmin. This suggests that the mechanism of control of the serum ceruloplasmin concentration may, normally, depend on the serum copper concentration.