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M Freitag

Publications and source records attributed to M Freitag.

87 records · Page 5Linked to original sources

Social network and social support predict improvement of physical working capacity in rehabilitation of patients with first myocardial infarction.

A cohort of 50 patients under 70 years of age who had suffered their first myocardial infarction (MI) entered an exercise-based rehabilitation programme. An extensive personal interview concerning psychosocial factors, including social network and social support, as well as an assessment of an array of clinical and laboratory variables was made before the patients were discharged from the hospital. A follow-up 6 months later of the 40 patients that completed the programme showed that material social support and social anchorage at baseline predicted improvement in physical working capacity, independently from age, gender and important clinical variables. The authors conclude that psychosocial factors could be predictors of equal importance as many of the standard risk factors and clinical assessments in the rehabilitation of a majority of post-MI patients. It is suggested that training programmes should provide opportunities for involvement of the patients' social network, in order to benefit from optimal social support during the rehabilitation process.

Adult↗

[Quantitative-morphometric characterization of the lung structure in congenital heart defects exemplified by Fallot disease and isolated ventricular septal defect].

The aim of this study was to investigate the possibility of determination of lung changes in congenital deformity of heart and vessels by the method of Weibel and Elias (1967) for count of points in the lung (volume of alveoli and interstitium). The results show that this method is suitable for the estimation of quantitative changes in Morbus Fallot. In order to decide the degree of arteriosclerosis an additional measurement of the wall thickness of lung vessels is necessary in cases of ventricular septal defect. The arteriosclerosis is an important factor for the secondary variations, especially of the right heart. A field of application of this method could be the praeoperative lung biopsy for the clarification of the question of operability.

Adolescent↗

[Blood pressure and heart rate behavior of ergometrically stressed patients with and without beta receptor blocker].

It is referred to the importance of bicycle-ergometric examinations for a better recognition of the hypertension with limiting value and the labile hypertension. According to time of day and the physical and psychic condition very different blood pressure values can be measured. Therefore, from this point of view blood pressure values may be compared only on the same exterior and interior conditions. The interior conditions are only little to be influenced. A standardized test method, as it is the bicycle ergometry, therefore under the same exterior conditions guarantees comparable and above all reproducible blood pressure values. Also the success of therapy under antihypertensive drugs and thus the prognosis can exactly be classified after these examinations. Furthermore it could be shown that the behaviour of the blood pressure under ergometric load with and without beta-receptor blocker is approximately the same.

Adolescent↗

Plasminogen activator inhibitor 1 activity and lipoprotein(a) in nephropathic patients with non-insulin-dependent diabetes mellitus versus patients with nondiabetic nephropathy.

Increased plasma activity of plasminogen activator inhibitor 1 (PAI-1) is considered as a risk factor for thrombosis associated with atherosclerosis by reduction of fibrinolysis. Since nephropathic patients with non-insulin-dependent diabetes mellitus (NIDDM) are a cardiovascular high-risk group, which has yielded only controversial results as to the regulation of PAI-1, we compared 19 overt nephropathic NIDDM patients (mean age 63 years, serum creatinine 1.9 mg/dl, proteinuria 4.2 g/day) to 17 nondiabetic nephropathic patients with various causes of renal insufficiency (mean age 63 years, serum creatinine 2.8 mg/dl, proteinuria 3.9 g/day). We found normal PAI-1 levels for patients with diabetic nephropathy and significantly elevated PAI-1 levels within the upper normal range for nondiabetic nephropathic patients. Common risk factors in both groups were very high levels of fibrinogen, lipoprotein(a), serum cholesterol, and LDL cholesterol.

Antithrombin III↗