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Biomedical subjects

M Freyer

Publications and source records attributed to M Freyer.

5 recordsLinked to original sources

[Behavior of ambulatory patients concerning the taking of medicine].

In 296 patients from a rural district the behaviour concerning the intake of medicaments was observed. After prescription of riboflavin-tablets over a period of 10 days three times an examination of the urine for signs of fluorescence was performed. Apart from this in a consultation of the physician finishing the test a control of not consumed remedies was performed. Hypertensive patients and patients with acute disease took the medicaments prescribed by the physician very unreliably. On the other hand, patients in the postconvalescence phase after myocardial infarction showed an essentially better intake discipline. In the majority of cases the irregular intake of medicaments was not admitted. A one time consultation on necessity and performance of the medicamentous therapy clearly increased the intake reliability during the examination period in a part of the patients.

Adolescent

[Tremor following intracerebral carbachol injection. 1.Carbachol sensitivity of various brain structures].

Tremor produced by intracerebral injection of carbachol. I. Susceptibility of different brain areas to carbachol Microinjections of carbachol into the lateral ventricle of rats caused tremor depending on dose. Intensity and duration of motor effects after injection of carbachol (30 mug/3 mul bilateral) into different brain areas were found to depend on localization: strongest tremor was elicited by injections into the nucleus caudatoputamen and cortex cerebri, moderate tremor by administration into the substantia nigra reticularis, globus pallidus and thalamic brain regions. Target areas of mean sensitivity were demonstrated in more rostral and caudal parts of the formatio reticularis. The injection of carbachol into the nucleus ruber, nucleus linearis and substantia nigra compacta brought about lowest tremor values. Ablation of the site of injection from the remaining brain abolished tremor induced by carbachol contrary to the tremor induced by oxotremorine.

Animals