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Biomedical subjects

M Friend

Publications and source records attributed to M Friend.

At least 19 recordsLinked to original sources
PubMed1998

Efficacy of zeta-cypermethrin as pour-on or spray formulations for the control of buffalo fly (Haematobia irritans exigua) in cattle.

OBJECTIVE: To determine the efficacy of zeta-cypermethrin in controlling buffalo fly (Haematobia irritans exigua). DESIGN: Five field trials in northern and central Queensland. PROCEDURE: Zeta-cypermethrin pour-on at 2.5 mg/kg, spray at 62.5 ppm, deltamethrin pour-on and pour-on vehicle were applied to groups of 20 cattle. Buffalo fly counts were conducted three times before treatment and 3, 7, 14, 21, 28 and 35 days after treatment. RESULTS: In central Queensland where synthetic pyrethroid resistance in buffalo fly populations was rare, 2.5 mg/kg of zeta-cypermethrin pour-on gave good control of buffalo fly for 4 weeks and was better than a deltamethrin product. A zeta-cypermethrin spray used at 62.5 ppm gave 14 days control. In far-north Queensland where resistance to synthetic pyrethroids and heavy rain was common, the maximum period of efficacy of zeta-cypermethrin pour-on was reduced to 2 weeks. CONCLUSION: In areas where there is low resistance to synthetic pyrethroids among buffalo flies, zeta-cypermethrin pour-on can be expected to give good control for 4 weeks.

Administration, Topical↗
PubMed1995

Characterisation of a membrane receptor on ruminants and equine platelets and peripheral blood leukocytes similar to the human integrin receptor glycoprotein IIb/IIIa (CD41/61).

This paper describes two anti-glycoprotein IIb/IIIa or CD41/61 murine monoclonal antibodies (Co.35E4 and Co.2oA1). The cellular distribution and apparent molecular weight of the antigen detected by these antibodies is consistent with their reaction with ruminant and equine glycoprotein IIb/IIIa. Biochemical analysis of the equine molecule using sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) revealed bands of 24, 100 and 110 kDa under reducing conditions and 115 and 80 kDa under nonreducing conditions. Biochemical analysis of ruminant antigen revealed that the 24 kDa band did not appear owing to the absence of labelling with sulpho-NHS-biotin. Co.35E4 and Co.20A1 recognised two different Ca2+ complex independent epitopes. The glycoprotein IIb/IIIa was present on ruminant and equine granulocytes, monocytes and platelets. However, binding on granulocytes and monocytes was due to the adsorption of membrane platelet fragments.

Animals↗
PubMed1995

A monoclonal antibody to swine erythrocytes recognizes the B blood group on the major glycophorin.

Recently monoclonal antibodies (mAbs) to swine red blood cells have been described. One of them (1AC11) was specific for the major swine glycoprotein with a molecular weight of 45 kDa and another mAb, 2G2, recognized the Ba allele in the B system of swine blood groups. Immunoblotting experiments to characterize the mAb 2G2 indicated that it reacts with an antigen of 45 kDa, present on the aqueous phase, glycophorin fraction, of swine red blood cells with the Ba allele and does not react with BbBb homozygous cells. The antigen recognized by 2G2 has the same characteristics as the major glycophorin recognized by 1AC11, so we can conclude that the B system of the swine blood group is on the major glycophorin of swine erythrocyte membranes.

ABO Blood-Group System↗
PubMed1994

A comparison of content-masking procedures for obtaining judgments of discrete affective states.

The purpose of this article is to investigate observers' use of acoustic cues to arrive at judgments of the speaker's affective state and to address current methodological limitations. Ninety-nine female undergraduates rated the level of excitement, happiness, and anger of speech stimuli under three content-masking procedures: low-pass filtering, random splicing, and reiterant speech. Each procedure preserves some forms of acoustic information while disrupting or degrading others. As predicted, the content-masking procedures generated bias in observers' affective ratings. Results are discussed in terms of the efficacy of the content-masking procedures and implications for the study of acoustic cues to speaker affect.

Affect↗
PubMed1992

Mouse monoclonal antibodies to swine blood group antigens.

Eight mouse hybridomas with haemagglutination capacity to swine blood group antigens were obtained, three of them producing antibodies capable of being used as blood group reagents. Two detected the Ba factor and another the Fa factor. The others gave non-specific and weak reactions or cross-reaction with antigens present in more than one system. We conclude that mouse monoclonal antibodies are also suitable for use in swine as a complement of polyclonal reagents.

Animals↗
PubMed1990

Red blood cell motion and hematocrit distribution in a deforming capillary.

Based on the relation between the red blood cell velocity and the blood velocity of the Fahraeus effect, we analyze the motion of a red blood cell in a deforming capillary to investigate how the ventilatory induced deformation affects the transit of the red blood cell through the pulmonary capillary and changes the hematocrit discharged from the capillary. An analytical solution is also obtained for the case of an infinitesimal deformation. The numerical and analytic solutions demonstrate that the variation in discharge hematocrit is proportional to the change of pulmonary capillary blood volume between the time that the red cell enters and the time that it exits the capillary. We also find that this hematocrit variation could be regarded, in terms of transport, to originate from the mid-section of the capillary.

Biomechanical Phenomena↗
PubMed1970

Polychlorinated biphenyl: interaction with duck hepatitis virus.

Ten-day-old mallard ducklings fed a polychlorinated biphenyl at concentrations of 25, 50, and 100 parts per million for 10 days suffered no apparent clinical intoxication. Five days later these birds were challenged with duck hepatitis virus, and they suffered significantly higher mortality than birds which were not exposed to the polychlorinated biphenyl.

Animals↗