[Evaluation of a rapid method for LH and FSH radioimmunoassay (author's transl)].
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Biomedical subjects
Publications and source records attributed to M Fukuchi.
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We have investigated the thyroid uptake of Tl-201 in 37 patients with various types of goiter, and in six with normal thyroids. Significant thallium uptake was found in all cases in which there was thyroid enlargement, including Graves' disease, toxic thyroid nodule, primary hypothyroidism, simple goiter, Hashimoto's disease, thyroid carcinoma, and thyroid adenoma. If goiter was absent, however, there was no demonstrable uptake--e.g., in secondary hypothyroidism, subacute thyroiditis, and the normal controls. Thallium uptake did not correlate with thyroid function tests such as BMR, T3-RU, T3, T4, TSH, antithyroid antibodies, or the 24-hr I-131 uptake. In 23 patients with diffuse goiter, on the other hand, maximum Tl-201 uptake correlated well with thyroid weight: r = 0.836 (p less than 0.001); y = 0.02 x + 0.06.
Before surgery, thallium-201 chloride detected a supraclavicular metastasis from a mixed follicular and papillary adenocarcinoma of the thyroid.
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Marked thyroid uptake of thallium-201 was observed in four patients with goiter, namely one case each of hyperthyroidism, primary hypothyroidism due to chronic thyroiditis, chronic thyroiditis in the mild hypothyroid state, and nontoxic nodular goiter.
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