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Biomedical subjects

M G Allen

Publications and source records attributed to M G Allen.

At least 19 recordsLinked to original sources

Utilization review of treatment for chemical dependence.

Utilization review of treatment for chemical dependence has become increasingly important as evidence accumulates that outpatient treatment can be effective in many cases. The authors discuss the basic questions that guide utilization review of treatment for chemical dependence, summarize research that has led to the increasing emphasis on outpatient and partial hospital treatment approaches, and review the American Psychiatric Association's guidelines for utilization review of chemical dependence treatment. Case examples illustrate issues in the treatment of adolescents, patients with dual diagnoses, and relapsing patients. The authors conclude that utilization review supports use of inpatient care only for patients who require intensive services, including those who are a danger to themselves or others, have serious physical or psychiatric disorders, or have not responded to an adequate trial of outpatient treatment.

Adolescent

Psychophysiological correlates of posttraumatic stress disorder in Vietnam veterans.

We measured event-related brain potential (ERP) component amplitudes and heart rate (HR) to four intensities of randomly presented tones in two matched groups of drug-free male Vietnam veterans: 12 patients diagnosed with posttraumatic stress disorder (PTSD) and 6 normal combat veterans. Subjects were evaluated with structured diagnostic interviews and anxiety and depression rating scales. We found a significant group X intensity interaction for P2 peak amplitude at CZ. Subjects were classified as augmenters or reducers: positive P2 slopes as a function of stimulus intensity implying augmentation and negative slopes implying reduction. Nine of 12 PTSD subjects were reducers (sensitivity of 75%) and 5 of 6 normals were augmenters (specificity of 83.3%). By the third and fourth second following tone onset, the mean HR of PTSD subjects increased more than twice that of the normals. HR change scores were significantly responsive to the manipulation of stimulus intensity and to the difference between our two groups. P2 reduction differentiates Vietnam veterans with combat-related PTSD from combat veteran controls, and PTSD subjects are more autonomically arousable than their combat veteran peers.

Auditory Threshold

Pathways between constitution and competence during the 1st 5 years of life.

A global measure of newborn constitutional adequacy was found to be positively related to competent functioning at the age of 5-6 years. In a sample of 15 boys and 5 girls, newborn constitutional adequacy was related to aspects of focused (versus unfocused) activity, outgoingness, cognitive and verbal ability, and motor skill at the early childhood follow-up. Additionally, some preschool data were available on most of the sample and continuity of competent functioning was traced across the 3 age periods. Also, hyperactive behaviors at the preschool period had negative implications for functioning in early childhood.

Child Development

Peer review of group therapy: Washington, D.C., 1972-1977.

The author discusses the evolution of psychiatric peer review in Washington, D.C. In its first six years (1972-1977) the Washington Psychiatric Society Peer Review Committee evaluated 146 cases, 23 (16%) of which focused on group therapy. Eight of these cases (35%) were partially or fully denied. Most of the cases involved outpatients with neuroses or character disorders who were treated in combined group and individual therapy. The author presents specific cases illustrating group therapy issues and peer review decisions. He discusses the benefits and liabilities of peer review and emphasizes its importance as a flexible, clinically sensitive, confidential, and meaningful process.

District of Columbia

A psychodynamically oriented group training program for early childhood care givers.

A training program for enhancing the care-giving qualities of child-care workers was developed and implemented through semistructured groups for family day-care mothers. The authors describe the theoretical orientation, program goals, and the outcome for trainees and trainers. Most impressive was the group process and content, which indicated the effectiveness of psychodynamically oriented program for care givers--people who ordinarly would not be expected to integrate such an experience successfully.

Adult

Twin studies of affective illness.

In a summary of the major twin studies of affective illness, there are significant differences between monozygotic (MZ) and dizygotic (DZ) concordance rates for both unipolar and bipolar illness, indicating the importance of genetic factors in the etiology of affective illness. However, since 28% of MZ twins are discordant for bipolar illness and 60% of MZ twins are discordant for unipolar illness, environmental factors are important as well. In addition, there is a significant difference between unipolar and bipolar concordance for MZ twins (although not for DZ twins). This supports other evidence that unipolar and bipolar illness are separate entities, and it suggests the possibility that genetic factors are more important in the occurrence of bipolar illness than in unipolar illness.

Affective Symptoms