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M G Castiglione

Publications and source records attributed to M G Castiglione.

17 recordsLinked to original sources
PubMed1993

Chlamydia trachomatis diagnosis: a correlative study of pap smear and direct immunofluorescence.

From June 1989 to September 1990, 255 women with recurrent vaginitis, were evaluated, at the "Service of Precocious Diagnosis and Therapy of Gynecological Tumor" of the 1st Department of Obstetrics and Gynecology. They were compared with a control group of 255 women selected in the same time. All patients between the ages of 18-40 years, with normal sexual behaviour, had a negative colposcopy for HPV and HSV2 infections. The cervical smear with Papanicolaou technique and direct immunofluorescence (DIF) was performed in all patients. The specimens were examined with a fluorescence microscope (Leitz). Positive determinations were confined by examination a tha magnification of 600 X. Slides were scored as positive if at least 5 distinct apple-green fluorescence-stained elementary body per field was observed. The two groups were entirely comparable in age, parity, method of contraception, and number of sexual contacts over the preceding three months. Our data confirmed a higher incidence of Chlamydial infections in women with recurrent vaginitis (34.1%) than in control group (8.23%). In symptomatic women, more cases of metaplastic cells with cytoplasmic vacuolation, less inflammatory alteration and a lack of specific agents like CA and TV, were found than in the control group. The DIF positivity, in both groups, was connected with a cytological findings of metaplastic cells with cytoplasmic vacuolation in 72.3% and 50% respectively.

Adult↗
PubMed1992

Prevalence of Parkinson's disease and other types of parkinsonism: a door-to-door survey in three Sicilian municipalities. The Sicilian Neuro-Epidemiologic Study (SNES) Group.

We investigated the prevalence of Parkinson's disease and other types of parkinsonism in a Sicilian population using a door-to-door two-phase approach. This design called for the administration of a brief screening instrument to all subjects who, on November 1, 1987, were residents of Terrasini (Palermo Province), Santa Teresa di Riva (Messina Province), and Riposto (Catania Province), Sicily (N = 24,496). Study neurologists using specified diagnostic criteria extensively investigated those subjects who screened positive. We found 63 subjects affected by Parkinson's disease, 21 with secondary parkinsonism, and seven with unspecified parkinsonism. The crude prevalence per 100,000 population was 371.5 for all types of parkinsonism and 257.2 for Parkinson's disease; for both entities, prevalence increased steeply with age and showed an inconsistent sex pattern. Our prevalence figures for Parkinson's disease are higher than those previously reported in Italy or elsewhere, which may be due, in part, to more complete case-ascertainment.

Female↗
PubMed1991

Are multiple domicile changes a risk factor for multiple sclerosis? A case-control study.

A retrospective case-control study was conducted to estimate the possible association between risk of multiple sclerosis (MS) and the number of changes in residence before the age 20 years. Forty-one patients and 82 controls were interviewed. Using the Mantel-Haenszel estimate of the odds ratio, no association was found between the number of moves and MS.

Adult↗
PubMed1991

A case-control study of amyotrophic lateral sclerosis.

A retrospective case-control study was conducted using 46 patients affected by amyotrophic lateral sclerosis and 92 closely matched healthy controls. Cases were ascertained through typical clinical and instrumental findings. Putative risk factors (bone fractures or major trauma, exposure to domestic animals, surgical operations, disease among first degree relatives and others) were investigated anamnestically using a standard questionnaire. Using Mantel-Haenzsel estimates of the odds ratio, no association was found between amyotrophic lateral sclerosis and the investigated variables.

Amyotrophic Lateral Sclerosis↗
PubMed1989

Amyotrophic lateral sclerosis in Palermo, Italy: an epidemiological study.

The incidence, prevalence and natural course of ALS were determined in the population of the province of Palmero, Italy. The average annual incidence calculated for the years 1973 through 1984, was 044./100.000 inhabitants. The prevalence rate on prevalence day December 31, 1984, was 1.67/100.000 population. The male/female ratio was 1.38. The mean age at onset was 54.3 +/- 11.02. The most common clinical form was the conventional one (61.4%); the bulbar form was more frequent among females than males. The mean duration of the disease was 33.7 +/- 35.8 months. The longest duration belongs to the pseudopolyneuritic form. The median survival was 36 months: 16 months for the bulbar, 36 months for the conventional and 51 months for the pseudopolyneuritic form.

Adolescent↗
PubMed1988

The application of F wave measurements in hepatic patients.

The ulnar and tibial nerve F response latencies were analyzed to study the proximal motor conduction velocity in 15 patients with liver disease. The results were compared with those obtained from 15 normal subjects. The tibial MNCV (P less than 0.01) and FWCV from spinal cord to elbow and knee for ulnar and tibial nerves (P less than 0.001) were significantly reduced in patients compared to the controls. Minimum, mean and maximum F latencies showed significant differences for ulnar (P less than 0.001) and tibial (P less than 0.01) nerves in patients with respect to the controls. The mean F determination compared to the minimum F and delta F did not improve disease identification. The conduction abnormality in hepatic patients appeared to be present only in the proximal segment of the ulnar nerve, whereas it was more uniformly distributed along the entire length of the tibial nerve. This demonstrates that the peripheral nerve involvement in hepatic disease is more diffusely present than can be determined by conventional conduction study only.

Adult↗
PubMed1986

Peripheral nerve involvement in chronic liver disease. Clinical and electrophysiological study.

A clinical and electrophysiological study was carried out on 19 selected patients with chronic liver disease. Clinical signs of peripheral nerve involvement were found in 4 patients (21%); while electrophysiological impairment was present in 11 patients (57.8%). These abnormalities were mostly limited to the sensory and motor fibers of the tibialis posterior nerve. Our data confirm the presence of peripheral nerve involvement in chronic liver disease, and that it may be evidenced by careful electrophysiological examination.

Adult↗
PubMedDate not supplied

[Description of a case of multiple sclerosis with psychotic disorders at the onset].

The authors report on the case of a woman, aged 29, who was suffering for 15 years from an unipolar manic psychosis and for 5 years from ataxia, speech troubles and urine incontinence. The diagnosis of MS was supported by the presence of a marked increase of liquoral IgG as well as Link's and Tourtelotte's index. CT scan, EEG and VEPs were normal. The relationships between the two clinical conditions are briefly discussed on the view of data of the literature.

Adult↗