Biomedical subjects
M G Christensen
Publications and source records attributed to M G Christensen.
[Femoral pseudoaneurysms in drug addicts].
Four cases of femoral pseudoaneurysms from substance abuse are presented. One patient, a 32 year-old women needed amputation (by disarticulation of the hip) after failed revascularization. Another patient had symptoms of claudication after triple ligation and resection without bypass grafting. The last two had an uneventful recovery: one after saphenous vein bypass, the other after simple resection and repair with a vein patch.
Revascularisation of atherosclerotic mesenteric arteries: experience in 90 consecutive patients.
OBJECTIVES: Visceral artery surgery is well known to vascular surgeons, but most have limited personal experience. We report our experience with 90 patients treated for atherosclerotic lesions of the visceral arteries during a 25-year period 1968-1993. DESIGN: Retrospective study. SETTING: Department of Vascular Surgery, University Hospital Rigshospitalet, Copenhagen, Denmark. MATERIALS: 54 women and 36 men, aged 56 (median; range: 34-78 years) underwent 109 consecutive mesenteric reconstructions. The indication in 90 primary procedures was acute mesenteric ischaemia of non-embolic origin in 25 patients, chronic ischaemia in 53 and prophylactic reconstruction in connection with aortic surgery in 12 patients. The superior mesenteric artery (SMA) was revascularised in 87 patients and the coeliac axis or common hepatic artery in six. Thus, only three patients had both territories revascularised. Thromboendarterectomy was performed in 15 patients, transposition of the SMA directly into the infrarenal aorta in 30 and bypass in 48 patients. CHIEF OUTCOME MEASURES: Cumulative symptom-free and survival rates. MAIN RESULTS: The overall perioperative (30 days) mortality rate was 13%, mainly caused by the high mortality rate of 44% (11 patients) in the acutely operated, as the mortality was 0% in patients operated on electively and only one out of 12 patients (8%) died after a prophylactic operation. Nine of the twelve deaths were due to progressive mesenteric infarction. Cumulated survival rates were 81, 60 and 35% after 5, 10 and 20 years, respectively which indicated a mortality rate three times that of an age- and sex-matched Danish population. During follow-up symptoms recurred in 30 patients, more often following emergency surgery and SMA transposition. CONCLUSIONS: Mesenteric revascularisation may yield long lasting results. However, surgery for acute ischaemia carries a high mortality rate, emphasising the importance of early surgery.
A phase III trial of zoladex and flutamide versus orchiectomy in the treatment of patients with advanced carcinoma of the prostate.
In a multicenter Phase III trial 264 patients with advanced prostatic cancer were randomized to either bilateral orchiectomy or treatment with zoladex supplemented by flutamide. Presently, median follow-up time is 30 months. A small difference in objective response was recorded in favor of the combination therapy, whereas no statistically significant difference was found in subjective response to therapy, time to progression, and overall survival. Adverse effects were more commonly encountered in the pharmacologically treated patients. It is concluded that the combination of zoladex plus flutamide is not clinically superior to orchiectomy in the treatment of patients with advanced carcinoma of the prostate.
Late recurrence of upper urinary tract urothelial tumours.
Two case reports of late recurrence of upper urinary tract urothelial tumours 13 years after ipsilateral local resection and 19 years after contralateral nephroureterectomy are used in the discussion on when to perform local resection. In accordance with existing literature we propose local resection in case of low-grade upper urinary tract urothelial tumours.
Functional bladder neck obstruction. Results of endoscopic bladder neck incision in 131 consecutive patients.
Endoscopic diathermy incision of the bladder neck was carried out as a routine procedure in 131 consecutive male patients with an established diagnosis of functional bladder neck obstruction. Follow-up after 3 months revealed excellent symptomatic and urodynamic results. Morbidity was low and the post-operative stay in hospital short (median 2 days). Patients must be informed of the risk of retrograde ejaculation associated with the procedure and objective evidence of the diagnosis is essential.
[Clinical diagnostic certainty in sprained ankles. A controlled blind study of 235 patients from a surgical outpatient department].
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[Intermittent drainage of the bladder in patients with indwelling catheters. A controlled study of the occurrence of bacteriuria following after Cystomat without irrigation].
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[Ureterolithiasis and reflux in a residual ureteric stump].
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[Complete suprapatellar rupture of the quadriceps].
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Pediatric anesthesia in the education of the SRNA.
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Using simulation to facilitate the acquisition of clinical observational skills.
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A model for the evaluation of allied health education.
The variety and complexity of evaluation designs, procedures and philosophies has proved confusing for educators and health practitioners. Many evaluation models do not provide for the scope of information needed by allied health programs and are inflexible in regard to the information needs of individual programs. The model presented here is based on the principles of "Systems Theory," which provides a comprehensive framework for the study of educational programs. Input, process, product and environment components are proposed as a method to study all aspects of program operations. With clearly definable rules for the evaluator and program decision-makers, the faculty can adopt and change the course of the evaluation as they work through the planning, implementation and recycling stages of the model. Use of the model should help programs identify information needs and bring existing evaluation efforts together under a comprehensive umbrella.
Impact of a life planning workshop on perceived locus of control.
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Professional development of nurse practitioners as a function of need motivation, learning style, and locus of control.
This study assessed the relationship of loci of control, learning styles, and motivational needs of 53 graduates of the Wichita State University Nurse Clinician Program to amounts and types of professional activities performed in a clinical setting. A self-appraisal was also considered in the analyses. Motivational needs assessed included the needs for achievement, affiliation, and power. Findings revealed that nurse clinicians with moderate need for achievement, high need for affiliation, and moderate need for power performed significantly (p less than .03) more professional activities than nurses with high need for achievement, low need for affiliation, and high need for power. Other findings showed a significant (p less than .04) negative relationship between chance locus of control and self-appraisals. Amounts and types of professional activities performed were not significantly related to loci of control or to learning styles.