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Biomedical subjects

M G Everitt

Publications and source records attributed to M G Everitt.

7 recordsLinked to original sources
PubMed1990

Exercise in leisure time: coronary attack and death rates.

Nine thousand three hundred and seventy six male civil servants, aged 45-64 at entry, with no clinical history of coronary heart disease, were followed for a mean period of 9 years and 4 months during which 474 experienced a coronary attack. The 9% of men who reported that they often participated in vigorous sports or did considerable amounts of cycling or rated the pace of their regular walking as fast (over 4 mph, 6.4 km/h) experienced less than half the non-fatal and fatal coronary heart disease of the other men. In addition, entrants aged 55-64 who reported the next lower degree of this vigorous aerobic exercise had rates less than two thirds of the remainder; entrants of 45-54 did not show such an effect. When these forms of exercise were not vigorous they were no protection against the disease, nor were other forms of exercise or high totals of physical activity per se. A history of vigorous sports in the past was not protective. Indications in these men are of protection by specific exercise: vigorous, aerobic, with a threshold of intensity for benefit and "dose response" above this threshold, exercise that has to be habitual, and continuing, which suggests that protection is against the acute phases of the disease. Those men who took vigorous aerobic exercise were demonstrably a favourably "selected" group; they suffered less of the disease, however, whether at low risk or high by the several risk factors that were studied. Men with exercise-related reduction in coronary heart disease also had lower death rates from the total of other causes, and so lower total death rates than the rest of the men.

Coronary Disease↗
PubMed1980

Vigorous exercise in leisure-time: protection against coronary heart disease.

1138 first clinical episodes of coronary heart disease (CHD) in 17 944 middle-aged male office workers in the Civil Service are reported. Men who engaged in vigorous sports, keep-fit, and the like during an initial survey in 1968-70 had an incidence of CHD in the next 8 1/2 years somewhat less than half that of their colleagues who recorded no vigorous exercise. The CHD rates of men who took such vigorous exercise were lower in both fatal and non-fatal clinical manifestations, though more so in fatal; throughout the age-range studied, though more striking in later middle age and early old age; and in all other sub-groups examined, including men with a family history of CHD, the obese, the short of stature, cigarette smokers, and men with severe hypertension and subclinical angina, as well as in those in favourable situations for CHD or neutral. The generality of the advantage suggests that vigorous exercise is a natural defence of the body, with a protective effect on the ageing heart against ischaemia and its consequences.

Adult↗
PubMed1976

Identification and treatment of arterial hypertension in general practice.

1. A screening programme has been set up in a group general practice for identifying and treating moderate high blood pressure in men and women aged 45-54 years, and at the same time the identification and treatment of high blood pressure in patients in reference general practices has been monitored. 2. The special measures resulted in a response rate of 68-8%. In the reference practices, 14-9% of patients attending during the study had their blood pressure reading recorded on the monitoring form. 3. The overall prevalence of diastolic blood pressure (phase 4) greater than or equal to 105 mmHg in the special hypertension programme is 3-8 times that observed in the reference practices.

Family Practice↗
PubMed1976

The relationship between blood pressure and biochemical risk factors in a general population.

The relationship between blood pressure, ponderal index, sex, blood glucose, haemoglobin, serum uric acid, calcium cholesterol and creatinine, and albumin has been examined in 698 subjects aged between 44 and 49 years from the register of a group general practice. Sixty per cent of the variation in systolic pressure could be explained by statistically significant associations with diastolic pressure, sex, blood glucose, serum calcium, and cholesterol. The diastolic blood pressure (not corrected for systolic pressure) was significantly related only to ponderal index, haemoglobin in men, and cholesterol in women. Pulse pressure was also positively related to the risk factors blood glucose, serum cholesterol, and calcium. The possibility is discussed that one or more of these variables reduce aortic compliance and that the serum calcium contributes to this end. Diastolic, but not systolic pressure, had a prime association with relative weight, obesity being only basically associated with an increase in diastolic pressure.

Adult↗
PubMed1975

High blood pressure. detection and treatment by general practitioners.

A questionnaire was sent to a 10% random sample of general practitioners in England and Wales on their attitudes to the detection and treatment of hypertension; 62% responded and no further inquiry was made. Their view on detection and criteria for treatment and investigations performed were considered in relation to their background. More of the older practitioners always measured blood pressure and 36% of all practitioners believed that hypertensive patients usually present with symptoms. Altogether 91% thought that strokes could be prevented by treating hypertension, and only 18% reported difficulty in keeping patients on treatment. Older practitioners preferred to measure the distolic pressure using phase five, while the younger preferred phase four. Nearly all doctors were satisfied with their current sphygmomanometers.

Attitude of Health Personnel↗
PubMed1975

Intraocular pressure and systemic blood pressure in the elderly.

The intraocular and systemic blood pressure, height, weight, and haemoglobin were measured in 573 subjects over 60 years old from a general practice population. Intraocular pressure was positively and independently related to systemic blood pressure (P less than 0.0001) and obesity (P less than 0.01) as assessed by the ponderal index. Systolic pressure rather than diastolic or mean pressure was most closely correlated with intraocular pressure and it is suggested that the systolic head of pressure increases the filtrated fraction of aqueous humour to cause a small but sustained rise in intraocular pressure. It is also suggested that obesity may decrease the facility of aqueous outflow.

Aged↗