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Biomedical subjects

M G Goetting

Publications and source records attributed to M G Goetting.

41 records · Page 3Linked to original sources

Tuberous sclerosis with cardiogenic cerebral embolism: magnetic resonance imaging.

A girl with tuberous sclerosis and intracardiac masses had at least two episodes of cardiogenic cerebral embolization, the attacks characterized by acute onset of prolonged neurologic dysfunction arising from different vascular distributions in both cerebral hemispheres. Renal embolization was suggested by hematuria. Magnetic resonance imaging (MRI) demonstrated ischemic lesions in cerebral locations predicted by the clinical signs. MRI also demonstrated extensive areas compatible with the dysmyelination of tuberous sclerosis.

Female↗

Regeneration in the cerebellum following methylazoxymethanol-induced destruction of the external germinal layer. Morphological and biochemical studies.

In the cerebellum external germinal layer (EGL) regeneration was maximal 10 days following methylazoxymethanol-induced destruction of the postnatal mouse EGL. Similar patterns of EGL repair and delayed disappearance were observed in both anterior and posterior cerebellar lobes. Final reduction in granule cell number to 30-50% of control exceeded the reduction in basket and stellate cells. Morphological changes in GABAergic cell populations were paralleled by alterations in glutamic acid decarboxylase activity. These studies suggest that the regenerating EGL may be similar to the normal EGL with respect to the emerging cell types, but that granule cells which develop later are less completely represented.

Animals↗

Intussusception encephalopathy: an underrecognized cause of coma in children.

Intestinal intussusception is a common cause of bowel obstruction in infancy and early childhood. Typically the presenting signs and symptoms are referable to the abdomen. On occasion the most prominent presenting feature is depressed level of consciousness. We describe 3 patients who presented with coma associated with intussusception.

Child, Preschool↗