Accreditation of laboratories.
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Biomedical subjects
Publications and source records attributed to M G Kerr.
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Temporal changes in sweat composition were studied in 4 horses during epinephrine (adrenaline) infusion (0.13 to 0.31 micrograms/kg/min for 3 hours), heat exposure (41 C, [33 C wet bulb] for 5 to 6 hours), and exercise (16 to 18 km/hr for 58 to 80 km). Four ponies also were studied during heat exposure. Sweat produced by each of the stimuli was hypertonic for Na+, K+, and Cl-. These electrolyte concentrations remained constant during the central period of the experiments, with changes occurring near the beginning and toward the end. The Na+ was significantly higher and K+ significantly lower in epinephrine-induced sweat than in heat-induced sweat, and the pattern of change in sweat Na/K ratio varied among the 3 stimuli. The Ca2+ concentration decreased with time and was hypotonic after 15 minutes of epinephrine-induced sweating. Concentrations of Mg2+ and protein decreased exponentially with time. There was a high correlation between them, although the Mg2+ was not protein-bound. Sweat urea concentration was directly related to plasma urea concentration. When plasma glucose concentration became greater than 10 to 12 mmole/L during epinephrine infusion, glucose appeared in the sweat and its concentration rose to 8 to 12 mmole/L of sweat when plasma glucose was more than 20 mmole/L.
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Simulated patients have been used to foster active learning and problem solving skills in an undergraduate programme of reproductive medicine. These simulators were trained to present a series of clinical problems and were used in a variety of approaches. They served to highlight communication skills and to force attention on the recognition, assessment and management of patient problems.
Our experience with laparoscopy as the primary means of assessment of the female genital tract is described in 279 women attending a subfertility clinic. Thirty-two per cent of patients with primary infertility and 60 per cent of patients with secondary infertility had significant pelvic disease. We feel that laparoscopy should replace other methods for the routine primary assessment of the genital tract in infertile women.
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