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Biomedical subjects

M G Randell

Publications and source records attributed to M G Randell.

4 recordsLinked to original sources

Immune-mediated vasculitis in five dogs.

Vasculitis was diagnosed in 5 dogs. Clinical signs varied, but all 5 dogs had signs of systemic illness. Inflammation and fibrinoid necrosis of small blood vessels were consistent findings. The skin and mucous membranes were the main tissues involved in 3 dogs; polyarthropathy and myopathy were diagnosed in 1 dog and myopathy in 1 dog. Good response to corticosteroid therapy was achieved in 3 dogs; in 2 dogs, immunosuppressive therapy with cyclophosphamide was necessary and the dogs responded well.

Animals↗

Hepatopathy associated with excessive iron storage in mynah birds.

Hepatic disease was diagnosed in 11 mynah birds. The most common clinical signs were dyspnea, weight loss, and abdominal swelling, usually accompanied by ascites. Radiography (9 birds) revealed hepatomegaly and ascites in most cases, and laboratory testing (6 birds) revealed hypoproteinemia and high activity of liver enzymes in all cases. Histologic examination (6 birds) revealed variable amounts of iron granule accumulation in hepatocytes, indicating hemochromatosis. Therapy consisted of administration of diuretics and abdominocentesis in dyspneic birds. All birds died, with survival time ranging from 1 day to 1 year.

Animals↗