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Biomedical subjects

M Galanda

Publications and source records attributed to M Galanda.

16 recordsLinked to original sources

[Personal experience with surgical treatment of the lumbo-ischiadic syndrome].

A prospective investigation of 200 patients with lumboischiadic syndrome, who were operated in the Regional Institute of National Health, Banska Bystrica. Before operation 176 patients had CT examinations and 70 perimyelographic examinations. Only patients where the clinical finding and CT or perimyelographic finding correlated were indicated for operation. Attention was focused on comparison of the findings on operation and findings of the CT examination. Noninvasive CT examinations which are aimed and follow a detailed clinical analysis and incl. sagittal reconstruction pictures give a reliable idea of morphological changes in the examined LS portion of the spine. They make it possible to localize herniation of intervertebral disc and to differentiate reliably compression of spinal roots by osseous structure in the area of facet, the narrow lateral recess or narrow spinal canal. Thus selective surgery is possible. Invasive perimyelographic examination is the method of choice where CT is not available or when the CT finding does not correlate with the clinical finding.

Adult

Behavioural responses to cerebellar stimulation in cerebral palsy.

Stereotactic placement of stimulating electrodes (TESLA) into deep regions of the cerebellum (Fischer instruments) was analyzed in respect to its organization into sagittaly oriented zones. This was done after imaging of the trajectory and target area and verification of the position of electrodes by CT (Siemens). A correlation was observed between the position of the stimulating electrode from the midline laterally and localization of induced responses on the body--from bilateral to ipsilateral. The combination of deep cerebellar stimulation and destructive method in the supratentorial region could be the optimal approach to relieve spasticity and to improve motor function in some cases of cerebral palsy.

Brain Mapping

Motor and psychological responses to deep cerebellar stimulation in cerebral palsy (correlation with organization of cerebellum into zones).

The study includes 68 cases of cerebral palsy stereotaxically operated on from 1977. Deep cerebellar stimulation treatment was performed. The motor and psychological responses to electrical stimulation of 305 points of subcortical regions of cerebellum, mostly lobus anterior were analysed. The characteristic response--slight motor jerk immediately--followed by relaxation and feeling of pleasure, even laughing, to the electrical stimulation from selected points was always found. The level of stimulating current must be adjusted individually. The higher current increased pathological posture, muscular tonus and was conducted with the state of fear. The lower current was without detectable influence on the patient. On the trajectory of electrode, nearly perpendicular to the sagittal plane were narrow areas, which recurred as the strips, from where it was possible or not to elicit characteristic response. The most convenient target is in the region of brachia conjunctiva cerebelli. Localization of the point of stimulation in respect to organization of cerebellum into sagittally oriented zones and the parameters of stimulation seem to contribute to the diversity of responses to cerebellar stimulation.

Adolescent

Stereotactic approach to therapeutic stimulation of cerebellum for spasticity.

A Stereotactic approach for transtentorial implantation of deep wire electrodes directly into the anterior lobe of cerebellum has been shown as a beneficial method for the treatment of cerebral palsy in 9 patients. Proper placement of the electrodes especially into the central lobule were checked by evoked potentials and by choosing an optimal program of therapeutic stimulation which appears to be essential. With its favourable effect particularly on axial musculature stimulation seems to promote physiologic maturation of functional mechanisms in the brain, which were delayed in the course of development.

Adolescent

Combined transtentorial dentatotomy with pulvinarotomy in cerebral palsy.

For frequently associated spasticity with involuntary movements in cerebral palsy operations on cerebellar nuclei or on the pulvinar of the thalamus are recommended. We combined both approaches in 45 patients. The combination was possible after experiences with transtentorial dentatotomy, in which the electrodes are introduced into the deep structures of the cerebellum from a burr-hole on the lambdoid suture. The same lambdoid approach may equally well be applied for introducing electrodes into the pulvinar of the thalamus. The lesion in the pulvinar may moreover be combined with the target in the centrum medianum or in the nuclei VIM-VCP or VOP. Lesions are always asymmetric and multilocular. Their influence on the clinical picture is quite favourable.

Cerebellar Nuclei

Some observations in treatment stimulation of epilepsy.

In a group of 10 patients suffering from epilepsy therapeutic stimulation was applied by means of chronic electrodes and a technical stimulator three times in nucleus dentatus, five times in nucleus caudatus, once in both structures simultaneously. Once chronic electrodes were introduced into the amygdalo-hippocampal complex and non-specific thalanic system bilaterally. One patient was stimulated by means of a pacemaker and once by normal rhythm from the hypothalamus of the same patient using magnetic tape. The patients were subjected to stimulations once a day for a period of 1-8 days. The results obtained are being discussed with respect to Goddard's kindling phenomenon.

Caudate Nucleus