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Biomedical subjects

M Galbussera

Publications and source records attributed to M Galbussera.

3 recordsLinked to original sources
PubMed1991

[Cystosarcoma phyllodes].

A rare case of mammary neoplasia is described. Its morphological and cytologic features are ascribed to cystosarcoma phylloides. It's a rare neoplasia since it represents only the 0.3-0.9% of mammary tumors. At present about one thousand of case have been described in literature. Because of its unforeseeable behaviour, cystosarcoma phylloides requires treatment and follow-up different from mammary carcinoma and fibroadenomas. The treatment is surgical only; the choice between an extensive exeresis and a complete mastectomy is related to tumor dimensions.

Breast Neoplasms↗
PubMed1986

Mechanism of the plasma cholesterol lowering effect of tazasubrate in rats: accelerated plasma cholesterol transport with increased liver lipoprotein receptor activity.

Tazasubrate (30 mg/kg/day) a new lipid lowering agent, chemically unrelated to fibrates, reduces plasma cholesterol in rats within 2-3 days to 50% of controls. During the early rapid decrease of plasma cholesterol, increased liver cholesterol concentrations are observed. These return to normal, once the new steady state of plasma cholesterol (at 50% of controls) has been reached. Radiotracer studies with 3H-cholesterol labelled plasma very low density lipoproteins are consistent with an accelerated plasma cholesterol turnover. Analysis of the binding to liver membranes of 125I labelled cholesterol rich very low density lipoproteins (beta-VLDL) shows a marked increase in the total binding (Bmax rising from 106 ng/mg of protein 378 ng/mg), without significant alterations in the receptor affinity.

Animals↗