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Biomedical subjects

M Galelli

Publications and source records attributed to M Galelli.

3 recordsLinked to original sources

A comparison of accuracy of computer treatment planning systems in brachytherapy.

An intercomparison was made between dose-rate point calculations with five commercial computer treatment planning systems used in brachytherapy. Sixteen Italian radiotherapy medical physics institutions performed a twofold test, respectively for point and linear sources, reproducing actual clinical implants and the results were compared to references values. The test was designed in order to determine the errors introduced separately by computation and by implant reconstruction via orthogonal films. The results show that for point sources a better accuracy can be achieved than for linear sources. It is also shown that a large variation of results exists between computation systems and the variability is larger for linear sources. The digitizing procedure adds a large amount of error. In the whole set of calculation points, the overall percent difference between computed and reference dose-rate values is larger than +/- 5% in 18% cases for point and in 52% cases for linear sources, with data input by digitizer. It seems that relevant errors do occur when computing actual dose rates, resulting in clinically relevant inaccuracies in the calculated absorbed dose and in its relative effectiveness.

Algorithms

Resampling algorithms for diagnostic radiology.

The use of digital image resampling can be highly suitable for diagnostic radiology. It can be applied not only to obtain zoom effects but also to solve various problems related to the comparison of images of different origin (NMR, CT, NM). The mathematical approach to this kind of algorithm, based on rational assumptions, can be very wide and diversified. In this work the principles of the stochastic and of the analytical methods have been analyzed. In particular, a complete mathematical treatment of the integral analytical methods, which are both the most theoretically interesting and analytically complex, has been performed. The practice of these techniques has to be determined each time from the analysis of the specific problem to which they are to be applied in the routine, and after a retrospective analysis of the results obtained.

Algorithms

[Simulation of an instrumental head for 6 MeV electron beam therapy].

Simulation of a therapy head for 6 MeV electron beams. We present the results of a simulation, performed using a Monte Carlo method, of depth dose curves in water for electron beams of initial kinetic energy of 6.4 MeV, generated by a radiotherapy microtron MM22 Scanditronix. The Fortran code in EGS4: comparison is made between simulated curves, obtained using various approximation criteria, and the experimental one.

Electrons