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Biomedical subjects

M Galletti

Publications and source records attributed to M Galletti.

6 recordsLinked to original sources
PubMed1989

[Screening of early color vision loss in diabetic patients].

Colour vision defects have been claimed to appear in diabetes before any retinopathy is visible. In the present study diabetic patients and non diabetic control subjects were screened with two different colour vision tests which include both red-green and blue-yellow parts, and are suitable for quantitative analysis of scores. The Lanthony 40 Hue test and the Tokyo Medical College--T.M.C. tables were used to assess colour vision in 106 diabetic (50 insulin dependent and 56 non insulin dependent) patients and in 99 non diabetic control subjects. Diabetic patients without visible retinopathy, familiar colour vision defects and/or lens changes, had significantly higher scores than control subjects in both eyes. The differences were more evident in non insulin dependent patients. Statistical analysis showed that early loss of colour vision was correlated with age and duration of diabetes for older patients, while correlation with glycosylated hemoglobin was moderately positive only for younger patients. Both tests (especially the Lanthony 40 Hue) resulted to be highly specific and could be used for the clinical study of colour vision losses in diabetic patients.

Adult↗
PubMed1985

Histopathological aspects of tissue reactivity to suture materials in microsurgical arterial, anastomosis.

In order to assess tissue reactivity to synthetic suture material in microsurgery, a histological study was carried out in 20 rabbits divided into two groups: "A" and "B". The aorta of the animals was sectioned and subsequently anastomosed using polyglycolic acid in the first group and monofilament nylon in the second group. The animals were sacrificed at 10, 20, 40, 60 and 90 days after surgery, and the specimens were studied both macroscopically and microscopically. Tissue reactivity during the initial 40 days had similar histological characteristics in both groups evidentiating a perisuture granuloma with macrophages and giant cells. The second period, 40 to 90 days after surgery, was characterized by a tissue reactivity specific for each type of suture. In group "A", the inflammatory process diminished in parallel to the absorbtion of polyglycolic acid with "restitutio ad integrum" of the vessel wall. In group "B", the inflammatory process persisted due to the presence of non absorbable monofilament nylon, thus causing a fibrosclerotic transformation of the vessel wall. The results of this study suggest that the most suitable suture material for anastomosing living tissues are absorbable sutures.

Animals↗