Biomedical subjects

M García de León

Publications and source records attributed to M García de León.

4 recordsLinked to original sources

PubMed1989

[Evaluation of the therapeutic effect of flumazenil in hepatic encephalopathy using cerebral cartography].

We investigated the therapeutic effect of flumanezil on acute and chronic hepatic encephalopathy in a group of cirrhotics; its efficacy was evaluated using clinical data and neurophysiologic examination, e.g. brain mapping. Flumazenil was not found to induce significant changes in the clinical status or in maps of the cerebral activity of patients with chronic encephalopathy. In acute encephalopathy, flumazenil improved clinical status, as was confirmed neurophysiologically by improved cerebral activity on brain mapping.

Acute Disease↗

PubMedDate not supplied

[Hemispheric differences in visual evoked potentials during the discrimination of consonants and signs].

Visual evoked responses were recorded in response to a series of consonants and non-linguistic signs randomly presented. We compared, with a sample of 16 young volunteers, P300 and N400 latency and amplitude in order to detect possible asymmetries. Results in amplitude showed a significant asymmetry within right hemisphere, both in P300 and N400 components. Latency results failed to present any significant difference during the discrimination of consonants, while non-linguistic signs discrimination reflect an asymmetrical tendency in P300 component.

Adult↗

PubMedDate not supplied

[Brain mapping studies in dyslexia].

Brain EEG mapping has been recorded during three different conditions, rest closed eyes, rest open eyes, and reading task, in a group of 22 dyslexic children, age mean 9.3 years, range 8-11, and control group of normal readers of the same age. All the subjects were right-handed, and laterality was assessed through the Edinburgh test. The individual maps in dyslexic and controls were averaged, and mean maps of both groups were obtained for a very different experimental condition. Rest closed eyes maps of dyslexics and controls disclose a powerful and symmetric alpha over occipital areas, with higher energy peak at 8.5-9.5 Hz., without significant differences in both groups. Brain maps centered in the fast beta band, 18-25 Hz., disclose significant differences in control group versus dyslexics, with more power in control group over all areas. Our findings suggest less adequate brain activation in dyslexics during reading tasks.

Brain Mapping↗

PubMedDate not supplied

[Study of cognitive functions in autistic children by means of electrical brain mapping].

Brain electrical activity of 20 autistic children and 19 controls, age range 7-13 years, was recorded employing brain mapping technics, during different test conditions: closed eyes, open eyes, listening music, puzzle task, receptive language, expressive language, writing and reading. The maps let us to analyze the differentiation and topographic organization of brain electrical activity, and the changes induced by psychological tasks over the different brain areas. The autistics children show, versus controls, slowed brain electrical activity, less organization and topographic differentiation, and also poor reactivity to the different test conditions in relationship with the ethiological diversity of this syndrome.

Adolescent↗