[An unusual cause of fever in Brittany].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to M Garre.
Explore the source record for details and available documents.
The authors prospectively studied the radiation doses to radio-sensitive organs secondary to bedside radiographs in intensive care patients and in a control phantom. Dosimeters were taped on different organs during each bedside X-ray. The mean radiation doses, expressed in 10(-5) Gy (m-rad), for an "average patient" who was hospitalized 9 days and had 6 chest X-rays were respectively: 292 to the sternal bone marrow; 239 to the thyroid gland; 3 to the testes; 1 to the ovaries; 605 to the eye for 2 maxillary sinus X-rays. No diffused irradiation was measured during a 2-month period in the intensive care unit nor on dosimeters worn by four nurses.
A fatal meningitis due to a spiramycin-sensitive group B Neisseria meningitidis occurred 13 days after interruption of a prophylactic antimicrobial therapy with spiramycin. The efficacy of recommended antimicrobial preventive treatment is discussed with regard to this case, other published cases and to the known partial and short term eradication of the naso-pharyngeal carriage of Neisseria meningitidis.
The authors report one case of psittacosis with acute respiratory distress syndrome, acute tubulo-interstitial nephropathy and jaundice. Erythromycin therapy was uneffective but recovery was obtained with minocycline and rifampicin treatment. Early diagnosis of Chlamydia psittaci infection is mandatory in order to prevent severe complications and to institute appropriate antimicrobial therapy.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A patient with AIDS developed local complications of BCG vaccination and disseminated chickenpox with severe pneumonia. This cas suggests that AIDS patients should not receive BCG vaccination and that adults with severe chickenpox should be investigated for LAV/HTLV III virus carriage.
Explore the source record for details and available documents.
The authors report a documented case of hyperphosphatemia-induced nephrocalcinosis after chemotherapy of an acute lymphoblastic leukemia (ALL). Microscopic examination of the kidney showed numerous calcium deposits with concentric structure in the calyces and in the tubules. Electronic microsound analysis proved the deposits to be composed of calcium phosphate. The nephropathy mechanism is studied, and a review of the 34 similar cases of this acute tumor lysis syndrome is made. Some suggestions are put forward to present the consequences of this therapy-induced syndrome.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Criteria defined by von Reyn were applied to 86 cases of bacterial endocarditis. Neurologic complications (NC) were categorized according to Pruitt definitions. Neurologic accidents were observed in 48 cases. They were the first clinical manifestation in 20 patients. Neurologic events were of poor prognosis in BE, mortality increasing from 26% in patients without NC to 83% in patients with NC (P less than 0.01). Two factors affect the incidence of NC: first, the location of endocarditis with 76% of NC in mitral valve endocarditis compared with 37% in other cases (P less than 0.005); and second the infecting organism: 71% of NC in staphylococcus aureus endocarditis versus 45% in endocarditis with other bacteria (P less than 0.02). Cerebral embolism was the most common NC (25 cases) related to an occlusion of the middle cerebral artery in 21 cases with a fatal outcome in 19 patients. Other NC included 15 intracranial hemorrhages with the evidence of an aneurysm in 4 cases, 6 septic meningitis, 2 macroscopic abscesses, and 2 multiple microscopic abscesses. This study emphasizes the high rate and severity of NC in staphylococcal mitral endocarditis despite antibiotic therapy and supports early surgery in this group of bacterial endocarditis.
Serum immunoglobulins and some complement components (C1q, C3c, C4, factor B, C9) have been evaluated in 99 malnourished patients. The sole abnormality which seems related to protein calorie malnutrition is a C1q decrease significantly correlated to serum albumin, thyroxin binding prealbumin and retinol binding protein. The immunoglobulins modifications seem to be related to pathological conditions associated with malnutrition (sepsis, liver diseases).
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The nutritional protein status of 260 unselected adult patients admitted to an internal medicine hospital unit and of 60 healthy controls was evaluated by measurement of the brachial muscular perimeter and of the weight--height ratio and by assay of serum albumin, prealbumin, retinol-binding protein and transferrin. The values most frequently low were those of retinol-binding protein (66%), prealbumin (42%) and albumin (25%). The sensitivity of short half-life serum protein assays is underlined. Twenty-eight p.cent of patients were found to have protein malnutrition on admission, most of these being women and patients older than 60 years. In view of the scattering of most values in controls according to age and/or sex, it is suggested that individual reference values should be determined for this type of study and that no comparison should be made with data found in the literature.
Post-traumatic chronic subdural haematoma infected by Salmonella sandiego is reported in a 55-year-old alcoholic man. Treatment involved a four-weeks' course of chloramphenicol and also subdural drainage. The patient ultimately recovered. Only four such cases have been reported in the literature. The mode of infection of the subdural haematoma is presumed to have been haematogenous in the absence of an otorhinological focus, meningitis or previous neurosurgery.