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Biomedical subjects

M Gharib

Publications and source records attributed to M Gharib.

At least 55 records · Page 3Linked to original sources
PubMed1986

[Bridging extensive esophageal atresias by a peritoneal transplant].

A method is presented that represents a modification of Rehbein's perlon filament technique for treating extensive oesophageal atresias. This new approach enables, in case of congenital oesophageal defects exceeding three vertebral bodies in length, to eventually perform end-to-end anastomosis of the patient's oesophagus. For this purpose, the distance between the mobilised oesophageal segments that are interconnected by means of a centrally positioned perlon filament, is additionally bridged over with a peritoneal cylinder in the sense of an autotransplant. The advantages of the method are the creation of a wide preformed channel for subsequent bougineages, the protective effect exercised on the mediastinum to prevent possible inflammatory conditions, and especially the continuous traction exercised on both oesophageal pouches by the shrinking of the transplant resulting in a ring-shaped stenosis that is easy to resect and can be bypassed via end-to-end anastomosis. We treated according to this method from 1982 onwards seven children with congenital oesophageal atresias extending over the length of three to seven vertebral bodies; four of these patients now present with patent oesophageal passage.

Esophageal Atresia↗
PubMed1986

[Comparative results of ileal conduit and colonic conduit. Analysis of 50 children with bladder exstrophy].

During the last 20 years 50 children with exstrophy of the bladder were treated in the Department of Paediatric Surgery of the Children's Hospital of Cologne employing besides other surgical methods such as primary closure, ureterosigmoideostomy, ureterocutaneostomy etc., in 15 cases an ileal conduit and in 12 cases a colonic conduit. These children could be followed up on the average 8.5 or 3 years after the operation, clinically, roentgenologically and in some cases via scintigraphy. Late complications requiring surgical correction, such as stomatostenoses, conduit elongation, stenoses of the ureterointestinal anastomosis, calculus formation in the conduit, or complications like ureteral reflux, recurring infections of the urinary passages with pyelonephritis, occurred only with ileal conduits, whereas no late complications requiring surgery were seen with the colonic conduits. Similar results in respect of late complications were found among the patients in Munich from 1955 to 1983 with 35 exstrophies of the bladder (13 ileal conduits, 1 colonic conduit) in which additionally an adeno-carcinoma was seen after ureterosigmoideostomy with fatal outcome. Hence, we are of the opinion that the method of choice is the preparation of a colonic conduit in patients with exstrophy of the bladder where primary closure is not possible because the bladder lamina is too small or already epithelialised. This approach offers the safest possible long-term protection of the primary normally positioned upper urinary tract.

Bladder Exstrophy↗
PubMed1984

Pituitary thyrotropic adenoma associated with congenital hypothyroidism. Report of two cases.

Two patients with congenital hypothyroidism and thyroid-stimulating hormone-secreting pituitary adenomas are described. Both patients had a history of long-standing, inadequately treated hypothyroidism accompanied by markedly elevated levels of serum thyroid-stimulating hormone. Pituitary tissue, obtained at autopsy in the first patient and at surgery in the second, disclosed a thyrotropic adenoma. Immunocytochemical studies with anti-thyroid-stimulating hormone antisera showed both tumors to be strongly immunoreactive. Such thyrotropic adenomas of the pituitary gland are presumed to occur as the result of protracted pituitary stimulation secondary to long-standing thyroid deficiency.

Adenoma↗
PubMed1984

Comparison of Ombrédanne's, Denis Browne's, and Cecil Leveuf's methods.

In the Department of Surgery of the Paediatric Clinic in Cologne, plastic reconstruction of the urethra was performed on 452 children over a period of 17 years. The use of Denis Browne's method, employed exclusively during the years 1963 to 1970, was associated with a much higher percentage of complications (56%) than was recorded during the subsequent period when alternative methods were used. The use of the surgical methods described by Ombrédanne and Cecil/Leveuf was followed by a drop in the rate of complications of 21% for the years 1970 to 1980. Based on the location of the urethral meatus, the patients were divided into three groups. The results obtained by using the methods of Denis Browne, Ombrédanne, and Cecil/Leveuf were then compared.

Child↗
PubMed1984

[Lobar emphysema].

The lobes most commonly affected are the left upper and the right middle lobes. The classical sign of respiratory distress is mainly found within the first two months of life. In 14 infants the diagnosis was confirmed by microscopic examination, 13 were treated by surgery and 4 infants, who had associated serious malformations or complications, died. In most cases hypoplastic bronchial cartilage of the concerned bronchi was seen, in some cases a stenosis of the lobar bronchi. It is of great importance to establish the diagnosis as soon as possible. The lobectomy is recommended if the respiratory or cardial failure is worsening despite artificial ventilation.

Bronchial Diseases↗
PubMed1983

Percutaneous nephroureteral drainage and stenting for postsurgical ureteral leaks.

Five patients with postoperative ureteral fistulae subsequent to surgically created ureteral anastomoses were treated successfully by temporary percutaneous nephroureteral drainage and stenting. Low, constant suction applied to the drainage tubes achieved total urinary diversion, while concomitant ureteral stenting seemed to prevent subsequent stricture formation. The techniques have reduced considerably the morbidity of this particular postoperative complication.

Adult↗
PubMed1982

[Operative correction of a urogenital malformation with persistent cloaca].

A case of malformation of the urogenital system with a persistent urogenital sinus and a cloaca is reported. There was unilateral agenesis of the kidney, megaureter and a double ureter with an ureteral orifice into the vagina and the clitoris. There was a double uterus and vagina with an orifice into the terminal gut. The patient had chronic recurrent urinary tract infections which required a colostomy during childhood. The operation largely restored a normal urogenital area and a functional anus.

Adolescent↗
PubMed1982

[Cryptorchism].

Explore the source record for details and available documents.

Age Factors↗
PubMed1982

[Abnormal choledocho-pancreatico ductal junction causative of cystic-cylindric dilatation of intra- and extrahepatic bile ducts].

During the last 5 years there were 6 patients found to have abnormal ductal junction of the choledochus into the pancreas. Clinical signs were: repeating upper abdominal pain, intermittent icterus, signs of pancreatitis and/or palpable tumor. Sonography is the initial examination to show up a dilatation of the intra- and extrahepatic bile ducts. But intraoperative cholangiography alone reveals the true condition of the choledocho-pancreatico ductal junction. Only after this procedure the therapeutic step of a choledocho-jejunostomy should be done.

Adolescent↗
PubMed1981

[Supracondylar humeral fractures in infants and small children].

The question of separation of the epiphyses in infants and small children of the type Salter-Harris affecting the distal humerus is discussed. The indications for open reduction of the distal humerus epiphyseal separation is rarely indicated and should only be utilised when there is associated injury to the nerves of vessels or a total disruption of the chondyle. Provided that accurate re-position and fixation can be performed, the prognosis of this injury is satisfactory.

Child, Preschool↗
PubMed1977

[Stomach duplication].

The eighty-four cases of stomach duplication known to date from world literature are presented including one case of the authors' own experience. The most varied theories of pathogenesis are discussed, as well as the very different clinical course the disease may take, and the diagnostic difficulties presented by X-ray examination. Finally, attention is drawn to the current use of the scintigraphy, which has broadened the diagnostic possibilities.

Humans↗
PubMed1976

[Traumatic subluxation of the head of the radius (author's transl)].

Radial-head subluxations were noted in 194 patients in the course of two years. It was more frequent in girls than boys (57.7% and 42.3%). The highest incidence was between the first and fourth year of life, with a peak in the first and second years. It no longer occurs after the seventh year. In 82.5% of cases the history was typical: a sudden longitudinal pull of the affected arm. In the remaining 17.5% no exact event could be ascertained. A questionnaire sent to the attending doctors provided replies in 82 cases (42.3%). Reposition by pull and pressure on the head of the radius, supination and acute flexing achieved repositioning in 92.7%, while in 7.3% repeat repositioning was necessary on the same or the next day. After successful repositioning complete absence of symptoms occurred in 98.8%. Incidence of recurrence was 30.5% during a follow-up period of up to a year and a half. The diagnosis had at first been had at first been missed 9.8% of cases.

Age Factors↗
PubMed1975

[Repair of prenatally ruptured omphalocele and the paraumbilical abdominal wall defect with the infant's own fetal membranes (author's transl)].

Since 1971, 35 children with prenatally ruptured omphalocele and paraumbilical abdominal wall defects were operated on in the surgical clinic of the Cologne Children's Hospital. 45.7% of them survived compared with 29.2% in earlier years. This improved chance of survival is attributed the use of the child's own fetal membranes.

Abdominal Muscles↗