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Biomedical subjects

M Gheorghiu

Publications and source records attributed to M Gheorghiu.

At least 55 records · Page 3Linked to original sources

[Carpal tunnel syndrome due to mycobacterium bovis BCG (author's transl)].

A 45-year-old woman, previously in good health developed chronic tenosynovitis with carpal tunnel syndrome a few weeks after wounding herself with a Pasteur pipette containing BCG cultures. She had received two injections of triamcinolone in the anterior annular ligament of the right carpa. The patient recovered after twelve months of antituberculous therapy associating isoniazid (300 mg/day), ethambutol (800 g/day), and rifampicine (400 mg/day). This is the first report of BCG tenosynovitis of the hand. The hazards of steroid injections into the tendon sheaths are pointed out.

Antitubercular Agents↗

Potency and suppurative adenitis in BCG vaccination.

Studies performed up to now in animal and man show that potent BCG strains guarantee a higher protection against tuberculosis than strains with weak virulence. Vaccine prepared from a strong BCG strain may be administered in lower doses, reducing the incidence of suppurative adenitis to a level acceptable by the individual patients and the health authorities.

BCG Vaccine↗

Facilitation through hyperventilation of therapeutic effect of pyrithioxin in cerebral infarct patients.

A method of treatment consisting in administration of a neurodynamic drug, pyrithioxin, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with hemiplegia. The combination was superior to pyrithioxin alone for the motor recovery of these patients. In some cases, it induced immediately a partial restoration of motility. The combination constantly brought about an increase in urinary excretion of norepinephrine and vanilmandelic acid, which failed to occur after pyrithioxin or HV alone. HV appears to facilitate the neural effects of the drug by promoting its transfer into the CNS.

Aged↗