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Biomedical subjects

M Goffart

Publications and source records attributed to M Goffart.

At least 19 recordsLinked to original sources

Concentrating capacity of the kidney and nitrogen partition in the urine in Perodicticus potto (Prosimii, Lorisidae, Lorisinae).

The concentrating ability of the kidney in Perodicticus potto was investigated. As the relation between this capacity and the thickness of the medulla has been stressed by Schmidt-Nielsen & O'Dell, the size of the various layers in the kidney was measured. Based on our observation that the potto may excrete uric acid in fairly high concentrations, the partition of nitrogen in the urine was also explored.

Animals

[Hypometabolism in Aotus trivirgatus (Primates, Plathyrhini, Cebidae)].

The standard metabolism of Aotus trivirgatus (Night monkey, Owl monkey) is 22.5 to 46.2 per cent below Kleiber's prevision curve for mammals, which applies to other cebid monkeys like Saimiri sciureus and Alouatta. However the metabolic rate of Aotus is not reduced to the extent found in two hypometabolic prosimians Perodicticus potto and Nycticebus coucang. The low metabolism in Aotus is associated with a normal body temperature and a thick fur of high insulating power. These results are discussed.

Animals

A duplex retina and the electroretinogram in the nocturnal Perodicticus potto.

The presence of cones in potto's retina has been proved beyond doubt although they are very restricted in number (1 cone for 300 rods). Morphologically, speaking there is no point in calling these cones "rudimentary" except for their slender outer segment. There are red sensitive elements in that retina at wavelengths beyond the spectral sensitivity of visual purple and it is tempting to assume that these elements are cones. The ERG evoked from these elements by red light differs from that in response to white and blue light. They dark-adapt faster than the receptors sensitive to blue and white flashes. However in some of their properties, for example fusion frequency, these cones behave like rods in other species. As these few cones seem to activate the bipolar cells nearly as effectively as the numerous rods, it is suggested that these cones may be responsible for day vision in the potto.

Animals

[Adrenosympathetic system and thermoregulation in a prosimian Perodicticus potto].

The urinary excretion of catecholamines in Perodicticus potto (1.76-2.94 mug/kg 24 h) is in the same range as in other mammals and the activity of the adrenosympathetic system does not account for the low metabolic rate in this species. The adrenals contain 1.140 +/- 0.14 mug A + NA/mg fresh tissue, of which adrenaline constitutes 94.5 per cent and are thus practically identical to those in Macaca irus. In a cold environment the daily urinary excretion of catecholamines of the tropical but cold hardy potto is only moderately increased.

Adrenal Medulla

[Electroretinogram in the nocturnal Prosimian Perodicticus potto].

There is histological evidence for the presence of cones in potto's retina: about 1 cone for 300 rods. The ERG of the dark adapted animal resembles that of the night monkey. In the potto's retina some red sensitive elements respond to wavelenghts beyond those which affect visual purple. The ERG evoked by these long wavelenghts differs from that produced by white light, suggesting a duplex character of the retina. These red sensitive receptors dark adapt faster than the others. However their fusion frequency is low, if compared with that in other species with a duplex retina. Nevertheless in potto the critical fusion frequency is higher for red light than for blue light.

Animals

[Dopamine of the caudate nucleus in Perodictious potto, Macaca mulatta and Macaca fascicularis].

The dopamine, dopac and tyrosinehydroxylase contents of the caudate nucleus in the prosimian Perodicticus potto and in the simii Macaca mulatta and M. fascicularis have been estimated. The results do not support the hypothesis according to which the sluggishness of the potto is somehow related to a low dopamine content of part of the extrapyramidal system as found in the Parkinson-syndrome.

Animals