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Biomedical subjects

M Gogora

Publications and source records attributed to M Gogora.

7 recordsLinked to original sources

[Angiodysplasia--a cause of severe hemorrhage in the gastrointestinal tract].

The authors describe a case of relapsing severe haemorrhage from angiodysplasias localized in the small intestine in an eighty-year-old female patient diagnosed only after probatory laparotomy. They discuss the diagnostic possibilities in angiodysplasia of the gastrointestinal tract and how it can be influenced by therapy. Even after resection of the affected portion of the intestine the formation of new angiodysplasias must be foreseen in previously intact areas and those can be the source of further severe haemorrhage.

Aged

[Fibrosing mesenteritis--a surgical problem].

The authors describe three cases of rare fibrotizing mesenteritis in adult patients. In two the aetiological agent was not detected, in the third one it was obviously talcum powder. The disease was manifested as acute abdomen or was detected accidentally. Compression of the visceral vessels caused the development of ischaemic foci with intestinal fistulae. Surgical treatment failed.

Adult

[Morphologic changes in chronic active superficial Campylobacter pylori-positive antrum gastritis after treatment with bismuth].

The authors investigated the effect of one month bismuth treatment (Bismuthi citrici 120 mg per capsule), 4 x 120 mg/day, on morphological changes of the gastric mucosa along with the effect on Campylobacter pylori (CP) in a group of 23 probands with histologically verified active superficial CP positive antrum gastritis. The probands suffered only from functional dyspepsia, to eliminate the action of other disease of the digestive tract on chronic gastritis. Complete eradication of CP occurred in 65.2% and disappearance of granulocytic infiltration as a manifestation of activity in 73.9%. The disappearance of activity correlated with the eradication of CP in 88.2. The authors evaluated also the degree of circular nuclear cellulization (grade 1-3). After one-month treatment it was reduced by 1 grade in 56.5% in the antrum, while in the corpus it remained unaltered in the majority. Complete histological normalization of the mucosa was not recorded.

Adult

[Crohn's disease of the stomach].

The authors describe the incidence of Crohn's disease at an uncommon site the stomach--in a 40-year-old man. With regard to the steadily increasing incidence of the disease, it is important to consider its presence also in uncommon sites in the gastrointestinal tract. The establishment of the diagnosis must be comprehensive, as even histological examination of endobioptic specimens or resected portions need not be unequivocal from the diagnostic aspect.

Adult

[Ischemic colitis as a localized manifestation of ergotism?].

The authors discuss a case of the development of ischaemic colitis in a 69-year-old female patient with superficial thrombophlebitis of the lower extremity treated by a combination of dehydrated ergot alkaloid Secatoxin forte drops with smaller doses of Heparin inj. After ruling out other causes of the development of ischaemia, the authors consider ischaemic colitis a local manifestation of ergotism.

Aged

[Incidence of chronic gastritis in young patients with functional dyspepsia].

The authors made during a 16-month period in 226 patients the diagnosis of functional gastric dyspepsia (144 women and 82 men aged 20 to 50 years). The differentiating criterion was a pathological organic finding in the upper part of the digestive tract, a pathological finding on the liver, gallbladder and pancreas as well as a pathological laboratory finding. The probands were divided by age into two groups and compared with a control group with similar differentiating criteria; however, the latter had no dyspeptic complaints. The differences in the incidence of chronic gastritis were not significant. From the investigation the following conclusions ensue: 1. Chronic gastritis is not the prerequisite factor of dyspepsia. 2. With advancing age the incidence of chronic gastritis increases. In group of men with functional dyspepsia and without it at the age of 35 years a normal antral mucosa is found only in 1/4 and a normal mucosa of the corpus in 1/2, whereby the corresponding figures at the age of 50 are 1/10 and 1/3. In the group of women with functional dyspepsia and without it at the age of 35 years a normal mucosa of the antrum is found in 1/3 and in the corpus in 2/3, the corresponding figures at the age of 50 years are 1/5 and 1/2. Under the age of 50 the authors recorded a higher incidence of chronic gastritis in the male population (antrum 96.1%, corpus 66.7%), as compared with women (antrum 76.9%, corpus 54.8%).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult

[Chronic active surface-positive Campylobacter antrum gastritis-- morphological changes 1 year after treatment with bismuth].

The works is based on a previous investigation published in the journal Vnitrní Lékarství, 36, 1990, 8, pp. 759-762. The authors investigated morphological changes of the gastric mucosa and the presence of Campylobacter pylori (CP) in probands with chronic active surface CP positive antrum gastritis one year after treatment with a bismuth preparation (Bismuth citrate 120 mg per capsule made on prescription) for a one-month period 4 capsules per day. This concerned probands with functional dyspepsia without a history of alcohol intake. After a one-year interval eradication of CP persisted in 8 probands (53.3%); in 7 patients (46.7%) there was a relapse of CP positivity. The authors confirmed that CP and active chronic gastritis are associated. Chronic non-specific inflammatory cellulitis persisted after one year with the same intensity in 17 probands (74%), in 6 it increased by one grade (26%). Improvement or complete recovery of the histological finding was not recorded in any of the patients. In the corpus of the stomach the unaltered finding persisted. Morphological changes were always directly proportional to the presence of CP. Its eradication appears to be causal treatment of chronic active surface CP positive antrum gastritis, one of the groups in the wide spectrum of chronic gastritis.

Adult