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Biomedical subjects

M Goos

Publications and source records attributed to M Goos.

At least 127 records · Page 7Linked to original sources
PubMed1987

[Goltz-Gorlin syndrome in a male].

Poikilodermal abnormalities with a linear or reticular distribution pattern and associated with other ectodermal and mesodermal disorders are characteristic features of Goltz-Gorlin syndrome (focal dermal hypoplasia), which is found mainly in females. In the light of recent literature a report is given about clinical aspects, histology, differential diagnosis, etiology, and especially the genetics of Goltz-Gorlin syndrome. Because of its rare incidence in males, a case of Goltz-Gorlin syndrome in a 21-year-old man is presented.

Adult↗
PubMed1986

[Internal disease findings in Arndt-Gottron scleromyxedema].

A case of papular mucinosis (scleromyxoedema of Arndt-Gottron) in a 64-year-old man is reported. Although a cutaneous mucinosis, the disease is characterized by a number of systemic disorders which determine the course and prognosis of the disease. A survey of 57 reported cases reveals that, in addition to the obligatory paraproteinaemia, neurological (24% of cases), cardiovascular (10%) and myopathic (9%) symptoms are in the foreground. Systemic lymphoplasmo-reticular involvement occurred in 14%. These findings emphasize the need for interdisciplinary cooperation in the diagnosis and for long-term supervision of patients with this disease.

Humans↗
PubMed1986

[Contact eczemas in housewives].

Housewives come into contact with a great number of irritating and allergenic substances on a daily basis. Contact dermatitis of the hands is a common result, caused more frequently by irritation than by allergy. In this review, the sources of contact allergens encountered in domestic work are shown and their relevance to sensitization and elicitation of hand excema is discussed.

Adult↗
PubMed1983

Phenotypic heterogeneity of leukemic Sézary cells.

Leukemic blood cells from eight patients with Sézary's syndrome were analyzed for enzyme cytochemical features, Fc receptors, and surface phenotype. Enzyme cytochemically the cases were heterogeneous in their activity of acid esterase, acid phosphatase and dipeptidylaminopeptidase IV (DAP IV). Only one case showed positive staining for DAP IV. The expression of Fc receptors for IgG and IgM also varied. The DAP IV-positive case exhibited Fc mu receptors. In contrast, four other cases showed only Fc gamma receptors. Analysis of the surface antigen pattern of Sézary cells with monoclonal antibodies revealed the phenotype of helper T lymphocytes (Leu-3 a/OKT4+) in all but one case. The Leu-3 a/OKT4-negative case showed a phenotypic feature of natural killer cells (Leu-7+). The results obtained with the antibodies TU14 and Anti-human Lyt-1 were more heterogeneous. The heterogeneity of Sézary cells may be interpreted as a sign of differences in functional differentiation or of proliferation of different T-cell subclones.

Acid Phosphatase↗
PubMed1983

Genetic heterogeneity of the ichthyosis, hypogonadism, mental retardation, and epilepsy syndrome. Clinical and biochemical investigations on two patients with Rud syndrome and review of the literature.

Major diagnostic criteria for the Rud syndrome are ichthyosis, hypogonadism, mental retardation, and epilepsy. Two unrelated patients are presented and compared with 28 reported cases. Genetical heterogeneity of the Rud syndrome is suggested by differences in clinical features, histological and endocrinological findings, steroid sulfatase activity, and modes of inheritance.

Child↗
PubMed1982

[In situ - demonstration of helper-T-lymphocytes in cutaneous malignant lymphomas by diaminopeptidase IV (DAP IV)].

Demonstration of helper-T-lymphocytes in tissue sections of cutaneous lymphomas by diaminopeptidase IV (DAP IV) gives new informations concerning the composition of these malignant infiltrates. It can be demonstrated that in plaque stage of mycosis fungoides the majority of T-lymphocytes are helper cells, thus giving evidence that mycosis fungoides represents a helper-T-cell-lymphoma. In tumor stage DAP IV activity changes, and the number of DAP IV-positive cells decreases remarkably. In malignant B-cell-lymphomas and high grade malignant lymphomas a small percentage of the infiltrate is composed of helper-T-lymphocytes; their existence was not known before. This method permits easy and reproducable identification of helper-T-lymphocytes in dermal infiltrates.

Dipeptidyl Peptidase 4↗
PubMed1982

[Chondroid syringoma].

Chondroid syringoma is a rare benign appendage tumor of the skin. Histologically, the tumor is characterized by the presence of sweat gland elements surrounded by a cartilage-like material. The lesions are most frequently located around the nose. Clinically, they appear as solitary, firm, circumscribed, slowly growing intracutaneous or subcutaneous nodules. In the majority of cases the clinical diagnosis is either basal cell epithelioma or cyst. This paper calls attention to the characteristic clinical features of chondroid syringoma as observed in five patients.

Aged↗
PubMed1981

[Skin manifestations in human yersiniosis (author's transl)].

Yersinia infections in 8 adults are reported. 6 patients had erythema nodosum, in 2 cases associated with maculo-papular rashes. In one patient an erythema multiforme-like rash was observed, in another one a papulo-vesicular rash. All patients were females. Yersinia infection was demonstrated serologically, in 3 cases also bacteriologically.

Adult↗
PubMed1981

Congenital erythroleukemia. A case report.

The disease of a four week old boy is described, which presented with papulous skin infiltrations, lethargy, anemia and bilateral testicular swelling. The investigation of bone marrow, cerebrospinal fluid and skin biopsy revealed infiltration by a leukemic process which could be identified by means of cytology and cytochemistry as erythroleukemia at the stage of erythremic myelosis. Death occurred 20 days after the onset of symptoms. Only one previous report of congenital erythroleukemia could be found in the literature. The findings are briefly discussed.

Biopsy↗