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Biomedical subjects

M Gow

Publications and source records attributed to M Gow.

7 recordsLinked to original sources
PubMed1985

Genome rearrangements of bovine rotavirus after serial passage at high multiplicity of infection.

After serial passage at high multiplicity of infection of standard bovine rotavirus in MA104 cells, different genome rearrangements occurred in which segment 5 was lost from the RNA profile and distinct additional bands of double-stranded (ds) RNA were found in positions on gels between segments 1 and 6. It was shown that some of the additional RNA bands contained segment 5-specific sequences. The additional RNA bands were transcribed in vitro to apparent full length. Analysis of the proteins synthesized in cells infected with viruses possessing rearranged genomes showed that in all cases the product of RNA segment 5, VP5, was missing; however, in one case an abnormal protein was observed which corresponded in size to the coding capacity of the mRNA transcribed from the additional genomic RNA band. Viruses with rearranged genomes could be plaque purified, and they grew in the absence of standard virus to titers comparable to those obtained from standard virus. In mixed infections of standard virus and virus possessing genome rearrangements, standard virus overgrew during passage at low multiplicity of infection whereas virus possessing genome rearrangements overgrew during passage at high multiplicity of infection.

Animals↗
PubMed1985

Stuttering and speech naturalness: some additional data.

Thirty listeners used the 9-point speech naturalness rating scale described by Martin, Haroldson, and Triden (1984) to score 1-minute spontaneous speaking samples from 15 normally fluent speakers and 15 stutterers who had completed the initial phases of a prolonged speech treatment program. The same listeners were later asked to judge whether each sample was from a stutterer or from a normal speaker. Reliable listeners identified almost identical numbers of samples from both speaker groups as "normal speakers," but the stutterers received significantly higher scores on the rating scale, indicating that their speech was judged more unnatural sounding. The speech samples incorporated those used in a related study by Ingham and Packman (1978), thus permitting a reevaluation of the findings of that study.

Humans↗
PubMed1980

The role of the children's nurse in the community.

In 1969 a pediatric home nursing service was started in Southampton to care for sick children at home. The primary role of the children's nurse in the community is discussed with particular reference to day case surgery, early discharge, care of the mentally and physically handicapped, pediatric medical care, prevention of a hospital admission, and care of the terminally ill. The secondary roles of teaching and liaison between the hospital and the primary health care team is discussed. After 10 yr experience with over 12,000 admissions to the day unit we believe that the majority of general surgical procedures such as circumcision, inguinal herniotomy, and orchidopexies can be safely undertaken on a day basis. The provision of adequate nursing care in the community which is closely linked with the hospital has been one of the main reasons for the success of the scheme.

Adolescent↗