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Biomedical subjects

M Gowardman

Publications and source records attributed to M Gowardman.

5 recordsLinked to original sources

Drinking by alcoholic patients following hospital admission.

Ad lib fluid intake of abstinent alcoholics and alcoholics in acute withdrawal exceeded that of psychiatric controls for 3 d following admission to hospital. The urinary output of abstinent alcoholics reflected their high fluid intake, but alcoholics in withdrawal displayed an initial oliguria. Routine blood and urine analysis did not provide any evidence of dehydration among alcoholics in withdrawal. Some possible causal factors contributing to a generalized alcoholic polydipsia are outlined.

Adult↗

Dibenzepin and amitriptyline in depressive states: comparative double-blind trial.

Dibenzepin and amitriptyline appeared to be equally efficacious in controlling target symptoms of depressive reactions. These results appear to be consistent with pharmacological profiles of the two drugs which are both tricylic compounds. Control of target symptoms occurred in an undulating and non-progressive manner in both groups. Aggravation of depressive symptomatology in the third week of treatment was noted in both groups and appeared to be clinically very important in the management of depressed patients. Dibenzepin caused relatively fewer side effects which appears to be an advantage over amitriptyline. Dibenzepin appeared to be a suitable alternative for amitriptyline intolerant patients, with moderately severe depression associated with anxiety, especially patients who demonstrated emotional sensitivity or passive dependent personality, and psychosomatic symptoms.

Adult↗