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Biomedical subjects

M Granić

Publications and source records attributed to M Granić.

29 records · Page 2Linked to original sources

Comparison of a perfusion syringe (Mill Hill Infusor) and a glucose-controlled insulin infusion system in the regulation of diabetes mellitus.

In a preliminary study, three unstable, juvenile diabetics were first connected to a glucose-controlled insulin infusion system (Biostator), and subsequently to a portable infusor (Mill Hill Infuser) for continuous subcutaneous insulin application. The levels of glucose and several other metabolites as well as the insulin requirement were compared. As a tentative conclusion, continuous subcutaneous application is recommended (1) for long-term therapy when several daily doses are required and (2) after metabolic compensation with a Biostator, but before conventional therapy.

Adolescent↗

Zinc and copper in the serum of diabetic patients.

The Zn/Cu ratio was examined in the serum of three groups of persons: healthy volunteers, diabetic patients on diabetic diet (NIDDM), and diabetic patients on diabetic diet and insulin (IDDM). Zinc, copper, the Zn/Cu serum ratio, and the blood glucose level were determined during fasting and 2 h after breakfast. Zn and Cu serum levels in NIDDM and IDDM patients were decreased. The Zn/Cu ratio was higher in both groups of diabetic patients. These changes in the Zn and Cu levels as well as in the Zn/Cu ratio were not related to chronic diabetic complications.

Blood Glucose↗

Insulin allergy.

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Adult↗

[The present status and perspectives of the University of Zagreb Medical School].

Ranked as the leading school of medicine in Croatia, University of Zagreb School of Medicine has succeeded to maintain the continuity of the high quality teaching process despite of the heritage of the socialist educational system and the harsh times of war. With the introduction of the six-year curriculum, where the "problem-solving" method is given prominence to, the school has fulfilled its requirements to meet the European standards of medical education. Teaching of the basic medical sciences is faced predominantly with the problems of obsolete equipment, whereas the quality of the education of the clinical subjects has not yet reached the desirable standards in all segments. Scientists from the University of School Zagreb of Medicine contribute to the overall scientific output of the Republic of Croatia with 10 to 20%, in addition to appearance of significant number of papers published in the international periodicals. According to the latest faculty roster, the number of full professors with teaching appointments is much too excessive. The University of Zagreb School of Medicine sees its main goal in the improvement of the quality of the teaching process. This goal is to be accomplished through introduction of the new courses (molecular biology, neuroscience, emergency medicine, ecology, medical economy etc.), improvement of the teaching methods, as well as through high standards of teaching the elective courses. Overall number of exams is also to be reduced in due time, whereas the future curriculum should provide a comprehensive medical teaching, with students actively participating in the teaching process through the first-hand experience with patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Croatia↗

[The femoral hypoplasia syndrome and unusual facies in an infant of a diabetic mother].

One-month-old female infant of diabetic mother with the femoral hypoplasia--unusual facies syndrome is presented. At birth the characteristic facial pattern of long philtrum with thin upper lip, micrognathia and cleft palate was present. Both legs showed extreme shortening of the upper segments. X-rays showed numerous skeletal abberations including radioulnar synostosis of the right elbow, dysplastic sacrum and hypoplasia of the femurs, the right one more severe. Radiological findings also revealed abnormal left kidney's collecting system and absence of the right kidney. Possible contributing factors to the pathogenetic mechanism underlying the skeletal defects in infants of diabetic mothers are considered.

Abnormalities, Multiple↗

[National organization of health care in diabetes based on the "Croatian model"].

This review article shows the development and organization of the "Croatian Model" of organization of health care for diabetic patients from Professor Vuk Vrhovac to this day, and its inclusion in the St. Vincent Declaration-a group of recommendations agreed upon in 1989 with the aim to decrease the morbidity and mortality of diabetes and its complications. The Model is organized on primary, secondary and terciary levels of health care. After the administrative changes of 1993, specialized health care for diabetic patients is delivered through County and Regional Centres for Diabetes and the Diabetes Reference Centre (the Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases), a scientific and educational institution and a WHO Collaborating Centre. Mention is made of the Croatian Diabetes Registry and statistical data on the morbidity (the prevalence of diabetes in Croatia is 2.37%) and mortality of diabetes mellitus and its complications, of organization of health care for diabetic patients, their medical treatment and care in Croatia.

Croatia↗