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Biomedical subjects

M Grosu

Publications and source records attributed to M Grosu.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[The etiopathogenesis of chronic hepatitis in children].

The authors study the etiology of chronic hepatitis, with emphasis on the high frequency of the infection with virus B, with a chronization rate of 15-20%. Taking into account the mother fetus, transmission and the increased number of AgHBs chronic carriers, with serious consequences on hepatic affection, the authors insist on the necessity of antiviral vaccination and of the therapy for virus elimination. At the same time, pathogenetic investigations are made for the presence of nonspecific antibodies and antibodies against hepatocytic membrane, elements which prove the permanent character of the hepatic lesions by immune mechanism, induced by the virus B persistence.

Antibodies↗
PubMedDate not supplied

[HBsAg carriers--a study performed on a closed collective of 0- to 3-year-old children].

The clinical, functional-histological and mainly the therapeutical aspect in chronic hepatitis, still raises important problems in children's pathology. As the clinical aspect of the chronic liver diseases is variable and less suggestive in the early and even advanced stages in children, the authors followed--for three years--the incidence of biochemical and histological functional disturbances in a closed collectivity of children. Since no specific therapeutical possibilities exist yet, the importance for a better knowledge of epidemiology of post-viral chronic hepatitis is emphasized.

Biopsy, Needle↗