Biomedical subjects

M Grudzień

Publications and source records attributed to M Grudzień.

At least 19 recordsLinked to original sources

PubMed1989

[Clinical aspects of peritonitis after cesarean section].

Caesarean sections complicated with peritonitis were analysed in a period of 10 years. In the whole group of 2238 caesarean sections done in the years 1977-1986 peritonitis developed in 8 cases (0.36%). In this group total or supracervical hysterectomy was done between the 4th and the 7th days of puerperium. Diagnostic difficulties in puerperal peritonitis and advantages of early surgical intervention for saving the life of the women in puerperium are stressed.

Adult↗

PubMed1989

[Influence of betamethasone on the vascular resistance in human placenta perfused in vitro].

The study was carried out on 48 human placentas perfused in vitro. Betamethasone was administered into the arterial system in the following single doses: 0.4 mg, 2 mg, 10 mg. It was found that betamethasone decreases the pressure of perfusion in different ways depending on the dose. A statistically significant decrease in perfusion pressure was observed in 30th minute of the experiment after administering 2 mg while a dose of 10 mg induced a significant perfusion pressure in 30th and 60th minute of the experiment. The relaxation of the blood vessels of the placenta under the influence of betamethasone was attributed to the action of dopamine on the dopaminergic receptors of the vessels and glucocorticoids modifying this action. The results of the experiments point to a positive action of betamethasone on the blood vessels of human placenta.

Betamethasone↗

PubMed1989

[Consumption of glucose under the influence of propranolol in human placentas perfused in vitro].

The consumption of glucose under the influence of various doses of propranolol in human placentas perfused in vitro was evaluated every 30 minutes during a two-hour perfusion. In the experiment the authors did not find a significant influence of propranolol on the level of the glucose consumption. The authors found a fourfold differentiation of glucose consumption between particular placentas. In the experiment these values differed from 2.63 mumol/g/h to 10.27 mumol/g/h.

Female↗

PubMed1989

[Influence of betamethasone on glucose consumption in the human placenta perfused in vitro].

The study was carried out on 48 human placentas perfused in vitro. Betamethasone was administered into the arterial systems in the following single doses: 0.4 mg, 2 mg and 10 mg. The authors found a highly significant or statistically insignificant decreased glucose consumption after administering each dose of betamethasone and at all times of the experiment. The phenomenon of a decrease in glucose consumption was attributed to an increased gluconeogenesis and releasing glucose from placental glycogen. The action of betamethasone consisting in supplying an increased amount of glucose is of great importance in the process of maturing fetal lungs in the uterus and in states threatening the fetus.

Betamethasone↗

PubMed1987