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Biomedical subjects

M H Forjaz

Publications and source records attributed to M H Forjaz.

6 recordsLinked to original sources
PubMed1998

Subcutaneous hyalohyphomycosis caused by Colletotrichum gloeosporioides.

The coelomycete Colletotrichum gloeosporioides was isolated in pure culture from subcutaneous nodules of the left forearm and elbow of a farmer after traumatic injury. To our knowledge, we report the first case involving this fungus as an etiological agent of subcutaneous infection. The in vitro inhibitory activities of amphotericin B, itraconazole, ketoconazole, miconazole, flucytosine, and fluconazole were studied.

Accidents, Occupational↗
PubMed1993

Agarose gel immunodiffusion tests with the addition of PEG (polyethylene glycol 6000) for the diagnosis and serological follow up of paracoccidioidomycosis infection.

By using PEG (polyethylen glycol 6000) in the gel immunodiffusion tests (ID), the precipitin lines were increased in 25.5% of the 192 sera reactions and the titers were increased from one to four serial dilutions in 44.6% of the 139 serum samples. Owing to its sensitivity, easy interpretation of the results and low cost, the use of 2% PEG incorporated into the gel in ID tests is recommended for the diagnosis and serological follow-up of paracoccidioidomycosis infections.

Follow-Up Studies↗
PubMed1987

Comparative study of tioconazole and clotrimazole in the treatment of tinea versicolor.

An eight-week comparative study of tioconazole and clotrimazole was carried out in 32 patients with tinea versicolor. Sixteen patients were treated with 1% tioconazole lotion and 16 with 1% clotrimazole solution; each drug was applied twice daily for 28 days. Clinical and mycological direct examinations were performed before treatment and on days 7, 14, and 28 of therapy. All patients underwent overall clinical evaluation 30 days posttreatment. At the end of the study, all patients were clinically and mycologically cured. During the second week of treatment, however, a significant remission in rash (P less than 0.05) was observed in the group treated with tioconazole. None of the treated patients had adverse reactions. Tioconazole is a new imidazolic agent with an intense fungicidal action. It has been found to be effective and safe and is an agent of choice for treating tinea versicolor.

Administration, Topical↗
PubMedDate not supplied

[Paracoccidioidomycosis in Brazilian Indians of the Suruí tribe: clinical-laboratory study of 2 cases].

Paracoccidioidomycosis has been considered the most frequent endemic systemic mycosis in Latin America. Although most cases of paracoccidioidomycosis involve rural workers, this systemic fungal disease has been scarcely reported among Amerindian populations from Brazil. We report two cases of paracoccidioidomycosis in Tupi-Mondé Amerindians from Cacoal, state of Rondônia, Brazil. Both cases exhibited positive serological results by a specific immunodiffusion test only when the assay was performed with antigens obtained from the mycelial form of P. brasiliensis. The authors present a literature review of paracoccidioidomycosis in Brazilian Amerindians and discuss the need for further investigations about the impact of the antigenic diversity of P. brasiliensis from different geographic areas on the serological diagnosis of PCM.

Adult↗