Biomedical subjects

M H Kottow

Publications and source records attributed to M H Kottow.

9 recordsLinked to original sources

PubMed1992

Classical medicine v alternative medical practices.

Classical medicine operates in a climate of rational discourse, scientific knowledge accretion and the acceptance of ethical standards that regulate its activities. Criticism has centred on the excessive technological emphasis of modern medicine and on its social strategy aimed at defending exclusiveness and the privileges of professional status. Alternative therapeutic approaches have taken advantage of the eroded public image of medicine, offering treatments based on holistic philosophies that stress the non-rational, non-technical and non-scientific approach to the unwell, disregarding traditional diagnostic categories and concentrating on enhancing subjective comfort and well-being, but remaining oblivious to the organic substrate of disease. This leads to questionable ethics in terms of false hopes and lost opportunities for effective therapy.

Complementary Therapies↗

PubMed1979

Informed consent.

Explore the source record for details and available documents.

Ethics, Medical↗

PubMed1979

Trabeculectomy with scleral wick. Technique and early results.

A variation to standard trabeculectomy is described, whereby the trabecular tissue flap is not completely excised, but dissected free, hinged at its nasal end and sutured diagonally across the scleral bed, to act as a wedge between the scleral flap and its bed, in an attempt to decrease the tendency of the sclera to scar into a watertight barrier. In addition, it is suggested that the trabecular flap acts as a wick that aids in the filtration of the aqueous humour. The technique has been used in 24 eyes with good to excellent, short-term, post-operative intraocular tension control in all but 2 patients. Mil complications like transient flat anterior chamber or blood cells in the aqueous occur at rates comparable to other filtering procedures.

Conjunctiva↗

PubMed1978

Experimental rubeosis of the iris in rabbits.

Rabbits were subjected to vascular injuries in an attempt to cause ocular ischemia and rubeosis. Occlusion of the ipsilateral common carotid artery showed fluorescein angiographic evidence of iris ischemia, but no rubeosis. Occlusion of two or more vortex veins caused iris ischemia, vasodilation, and angiographically visible neovascular capillaries on the iris. Histology confirmed the presence of thin-walled, superficial neovascular channels. The stimultaneous occlusion of the carotid artery and of two or more ipsilateral vortex veins also produced angiographic and histologic evidence of iris ischemia and neovascularization. These results confirm that venous flow impairment is a more efficient stimulus to neovascularization than ischemia due to arterial insufficiency. Nevertheless, in none of the animals could a neovascular response comparable to human rubeosis be elicited, and it is concluded that vascular lesions to the anterior segment are not an adequate model to study rubeosis.

Animals↗

PubMed1978

Anterior segment fluorescein cineangiography.

We have developed a technique for performing anterior segment fluorescein cineangiography. Illumination is obtained with a halogen lamp of a standard slide projector that is fitted with a blue excitation filer. Cinematography occurs with a movie camera fitted with an absorption-type barrier filter and mounted to a photo slit lamp through a cineadapter. The technique has been successfully employed with animals, and it is anticipated that the light levels used are tolerable and safe for application with humans.

Animals↗

PubMed1978

Consensual reactions to anterior chamber paracentesis in the rabbit.

A consensual reaction was consistently obtained in rabbits subjected to unilateral paracentesis. On fluorescein angiography of the anterior segment, we observed that this consensual reaction consisted of a slight to moderate dye extravasation from the ciliary processes into the aqueous. Aspirin usually, but not always, inhibited this reaction. Retrobulbar injection of anesthesia to the injured eye always blocked the consensual response, as did phenoxybenzamine injected intravenously before the paracentesis. We concluded that consensual responses are more efficiently inhibited by nerve-blocking agents than by prostaglandin inhibitors. These results suggest that the interocular pathway mediating consensual responses is probably neural and not caused by prostaglandins released into the general circulation.

Animals↗

PubMed1978

When consent is unbearable--a case report.

Informed consent has become one of the central problems in medical ehtics. At first sight, it would seem that no argument can be made against a person's right to be fully aware of the extent, course, and implications of his medical condition. It seems equally obvious that it is the patient's right to participate in, influence, or fully and solely assume the decisions of medical actions that should be undertaken or withheld with regard to his disease. Nevertheless, there are circumstances in which these commonly held assumptions about a patient's rights may not apply. It is the purpose of this report to describe a case where informed consent was deliverately not sought, and to discuss the ethical issues involved.

Adenocarcinoma↗

PubMed1978

Congenital malformations of the retinal vessels with primary optic nerve involvement.

3 cases with various degrees of racemose hemangiomata of the retinal vessels are described, in whom the optic nerve showed primary involvement. The vascular malformation ranged from multiple arteriovenous shunts (2 cases) to marked vascular tortuosity, and the optic nerve showed involvement that varied from severe hypoplasia with blindness, to normal appearance with campimetric enlargement of the blind spot. The combined malformation must be placed at the 110-mm embryonic stage, and the tissue primarily involved is the vascular tree branching from the developing central retinal artery at the end of the 4th month. The vascular anomaly, in turn, causes underdevelopment of optic nerve tissue and involvement of the bony orbit.

Adult↗

PubMedDate not supplied

Persistent hyperplastic primary vitreous in an adult: case report with fluorescein angiographic findings.

The clinical features and fluorescein angiographic findings of an 18-year-old man with PHPV are reported. The case is unusual in that the eye survived into adulthood. The lens resorbed spontaneously, thereby permitting study of the retrolental mass by fluorescein angiography. Fluorescein leakage from the persistent vessels was very slow but present, thus indicating a probable disruption of the endothelial tight junctions of the tunica vasculosa lentis.

Adolescent↗