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Biomedical subjects

M H Leonard

Publications and source records attributed to M H Leonard.

At least 19 recordsLinked to original sources
PubMed1996

Mammoscintigraphy with technetium-99m-sestamibi in suspected breast cancer.

UNLABELLED: Our goal was to determine the clinical usefulness of 99mTc-sestamibi to identify breast cancer in patients prior to biopsy. METHODS: We studied 66 patients who received 20 mCi 99mTc-sestamibi intravenously. Lateral and anterior planar images were gathered within 30 min of the injection. Only focal increased uptake was interpreted as positive. Confirmatory pathologic diagnoses were obtained within 2 mo. The prevalence of breast cancer in our sample was 54%. RESULTS: We report an overall sensitivity of 83% and specificity of 93% for the diagnosis of breast cancer. In palpable lesions, the sensitivity was of 94% with a specificity of 91%, while in nonpalpable abnormalities the sensitivity was of 64% with a 100% specificity. Six patients with a malignancy had negative scans, four of these lesions were nonpalpable. Only two of 31 patients with benign lesions had an abnormal scan. CONCLUSION: Mammoscintigraphy with 99mTc-sestamibi has high specificity and adequate sensitivity for the noninvasive diagnosis of breast carcinomas.

Adult↗
PubMed1982

Tenosynovitis due to incense.

A 16-year-old girl accidentally incurred a puncture wound on an incense cone. The incense, like other ligneous materials, irritated the soft tissue and predisposed the radial bursa of the forearm to infection. The infectious organisms produced gas that was visible on roentogenographic examination. This caused concern until to Clostridia could be found in the wound. The bursal opening, secondary closure, and antibiotics produced a satisfactory result.

Adolescent↗
PubMed1976

Open reduction of fractures of the neck of the proximal phalanx in children.

Fractures through phalangeal necks of proximal phalanges in children, which are angled so as to produce a dislocation or subluxation at the next distal joint, require open reduction. The technique includes a zigzag incision, a splitting of the extensor tendon, and the use of crossed Kirschner wires of .035 mm. Infections have not occurred from allowing the wires to protrude through the skin. The end results are better than those reported from conservative management of this fracture. The earlier the surgery the better the end results.

Adolescent↗
PubMedDate not supplied

Patterns of fluid accumulation in splenic trauma: demonstration by CT.

Detection of hemoperitoneum in splenic trauma is as important as detection of the visceral injury itself. Observation of a consistent spectrum of fluid accumulation in patients with splenic trauma prompted us to investigate the patterns in more detail. Twenty-three computed tomographic (CT) scans in 20 patients were evaluated with respect to presence of fluid collections in various peritoneal and retroperitoneal compartments. These were correlated with severity of injury and operative and pathologic findings. Hemoperitoneum was detected in the pelvis (65%), paracolic gutters (52%), left subphrenic space (48%), perihepatic space (48%), Morison's pouch (17%) and in the lesser sac (9%). In addition to free fluid, pleural fluid (39%) and retroperitoneal hematoma in the left anterior pararenal space (13%) were also encountered. These ancillary findings may help to substantiate the diagnosis of splenic trauma in equivocal cases, particularly when the spleen itself is obscured by artifacts. Early detection may reduce mortality and morbidity associated with splenic trauma.

Hemoperitoneum↗
PubMedDate not supplied

Superior entrapment of the clavicle.

Three degrees of acromioclavicular separation are commonly recognized. A Type III separation with entrapment of the clavicle on the top of the acromion is frequently not recognized while in its acute phase and amenable to closed reduction. The sign of this type of acromioclavicular separation is an apparent Type III in which one cannot manipulate the clavicle. The acute case is treated by local anesthesia, manipulation, and splinting. The chronic case is treated by excision of the outer end of the clavicle. In 1979 we treated three acute and one chronic superior entrapment of the clavicle on the acromion. During this time interval 67 acromioclavicular separations of Grade I, II, and III were treated. This amounted to 6% of our acromioclavicular separations treated during 1979.

Adult↗