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Biomedical subjects

M H Mason

Publications and source records attributed to M H Mason.

6 recordsLinked to original sources

The Caring Program for Children. The Michigan experience.

Public-private partnerships may offer the best opportunity in the near-term for addressing the problem of the uninsured. In Michigan, a broad spectrum of groups has studied the issue of the uninsured and, despite the diversity of the groups, arrived at a consensus that providing coverage to uninsured children is an urgent priority. The Caring Program for Children, a private program initiated by Blue Cross of Western Pennsylvania to provide primary and preventive health care coverage to children in low-income, uninsured families, gained support from the Michigan legislature and advocacy and provider groups as a means to address the problem. Blue Cross Blue Shield of Michigan and the Michigan Department of Social Services joined to expand the Caring Program for Children from a private program to a public-private venture funded by federal and state funds and private donations that has the potential to provide coverage to more than 12,000 children. The Michigan experience may be instructive to other states attempting to devise immediate local solutions to the problem of the uninsured.

Adolescent

Ovarian metastases from colon carcinoma.

A case report describes a postmenopausal woman who presented with vaginal bleeding and a pelvic mass. She was found to have a colon cancer with a large metastasis in the right ovary. A review of the literature suggests that ovarian metastasis from a primary colon carcinoma is not rare. Frequently, the ovarian tumors causes symptoms sooner than the primary carcinoma. The presence of ovarian metastasis is associated with a poor prognosis. Consideration should be given to the performance of prophylactic oophorectomy during colon resections for carcinoma.

Adenocarcinoma

Ameloblastic fibrodentinoma: report of case.

The classification, progression, and treatment of the mixed odontogenic tumors remain controversial. In the case reported here, examination of a patient who presented with delayed eruption of a primary central incisor led to the discovery of an impacted incisor and an associated isolated radiolucency.

Child, Preschool

Evaluation of a bioassay method for serum amikacin concentrations.

The bioassay system from American Diagnostic for amikacin was compared to the same company's radioimmunoassay (RIA) technique used in this hospital. The bioassay is performed by adding serum from a patient to wells cut in agar which have been seeded with a susceptible fast growing microorganism (Enterobacter). After incubation of five hours at 37 degrees, the zones of inhibition for four standards are measured and plotted. The amount of amikacin in the serum sample is then determined from the linear graph. Ten replicates of a serum with 8 microgram per ml of amikacin and 10 replicates of a serum with 20 microgram per ml of amikacin were assayed on each of four days. Aliquots of the same samples were assayed in a similar manner by RIA. The coefficients of variation (CVs) of the within run assays by the bioassay and RIA methods for the low amikacin test sample ranged from 4.7 to 7.2 percent and 6.2 to 13.0 percent, respectively. The within run CVs for the high amikacin test sample for the bioassay and RIA methods ranged from 5.2 to 6.9 percent and 5.0 to 13.9 percent, respectively. The day to day and overall CVs for the bioassay and RIA methods for the low amikacin test sample were 1.5 and 5.8 percent and 7.4 and 11.8 percent, respectively. For the high amikacin test sample, they were 0.4 and 6.0 percent and 4.0 and 9.6 percent, respectively. The correlation coefficient for 49 sera from patients on amikacin was 94 percent between the two methods.

Amikacin