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Biomedical subjects

M H Meyers

Publications and source records attributed to M H Meyers.

14 recordsLinked to original sources

Closed biopsy of musculoskeletal lesions.

Five hundred and thirty-one closed biopsies have been done in our general hospital since 1967. Four hundred and eighty-four were for lesions of bone and forty-seven were for soft-tissue lesions. More than half of the lesions were infections or nonspecifically reactive. The procedure was done under local anesthesia in 73 per cent and roentgenographic or image-intensifier control was generally required. The Craig needle was used for cancellous bone near vital structures; the Michele trephine, for cortical or sclerotic bone at a distance from vital structures; and a special needle was used for soft tissue. Closed biopsy provided an adequate specimen that was accurately diagnosed in 66 per cent of bone lesions and in 76 per cent of soft-tissue lesions. This compared favorably with both aspiration and open-biopsy success rates reported by others, and was accompanied by a 1 per cent complication rate, mostly neural and mostly in association with vertebral lesions.

Biopsy

Osteotomy for tibia vara in Paget's disease under cover of calcitonin.

Five women with Paget's disease of the tibia were seen with pain in the knee, ankle, or both, as well as with tibial bone pain. All had tibia vara and internal torsion of the tibial shaft. Osteotomy to correct the deformities was preceded by a course of calcitonin which relieved the bone pain but did not relieve the articular pain. Relief after satisfactory correction of the tibial deformity was achieved in all patients. Calcitonin effectively minimized bleeding at the osteotomy site and complications were not encountered.

Aged

Determination of the vascularity of the femoral head with technetium 99m-sulphur-colloid.

The results of technetium 99m-sulphur-colloid scans performed at the Los Angeles County-University of Southern California Medical Center and Rancho Los Amigos Hospital to assess the vascular status of the femoral head after sixty-five displaced and thirty undisplaced fractures of the neck of the femur and forty-four traumatic hip dislocations as well as in fifty patients with idiopathic ischemic necrosis of seventy femoral heads were evaluated by histological and clinical examination after follow-up of two years or more. The accuracy of the scan as corroborated by the histological findings and clinical results was 95 per cent. The method is safe, reliable, accurate, and simple in contrast to other methods which have disadvantages related primarily to technical complexities, difficulty in interpretation, and expense.

Biopsy

Total hip replacement in renal transplant recipients with aseptic necrosis of the femoral head.

Aseptic necrosis of the femoral head is a complication of renal transplantation which seriously delays the rehabilitation of the patient despite otherwise successful transplantation. Of 187 renal allograft recipients, 8 underwent 14 total hip replacements. The most severe postoperative problem was an easily reducible dislocation. All patients were relieved of their severe preoperative pains and all were greatly improved in mobility and strength. Renal function was not altered in any patient. It is therefore suggested that total hip replacement be recommended in such cases at an early stage so that the patient may be spared prolonged suffering and may be returned to a programme of post-transplant rehabilitation.

Adolescent

Collateral ligament laxity of the knee. Long-term comparison between plateau fractures and normal.

Bilateral varus-valgus knee-stress roentgenograms were made in 208 patients with unilateral single tibial-plateau fracture. Martin's so-called clear space was used to measure the laxity of the collateral ligaments and statistical analysis showed no increased laxity in the possibility injured ligaments. A vacuum phenomenon was produced in 36 per cent and ligament calcification was noted in 16 per cent of the knees tested.

Adolescent

Traumatic dislocation of the knee joint.

The results in thirty-three of fifty-three traumatic dislocations of the knee followed for more than one year confirmed our conclusion, made in 1971, that early repair of all torn ligaments gives the best results, and that the vascular status following this injury must be observed carefully since vascular repair or thrombectomy within eight hours of injury gives the best chance of preventing gangrene of the leg. The twenty associated fractures in these thirty-three patients were treated successfully with conventional methods, except for three displaced fractures of the medial tibial plateau in which closed reduction failed and internal fixation was required.

Femoral Fractures

Isolated avulsion of the tibial attachment of the posterior cruciate ligament of the knee.

Of fourteen isolated avulsion fracutres of the posterior tibial attachment of the posterior cruciate ligament, one was undisplaced and five were minimally displaced. These six were treated conservatively, but four of the five displaced avulsion fractures progressed to non-union and significant functional disability. Eight displaced avulsion injuries were treated by open reduction. In four knees the fragment was sutured back to its origin on the posterior superior aspect of the tibia, and three of the these united. In two knees the fragment was large enough to fix with a screw and union ensued. There was excellent functional capacity in five of the six that united. The other two displaced fractures, treated three and seven months after injury, had open reduction and the fragments were sutured to the tibia in an advanced position. Union was obtained in both with good functional capacity.

Adolescent

The treatment of osteonecrosis of the hip with fresh osteochondral allografts and with the muscle pedicle graft technique.

Osteonecrosis of the hip in Stages 1 and 2 are treated by conservative measures such as rest, aspirin, and a cane. If activities of daily living are impaired or stronger analgesics become necessary the muscle pedicle graft is advised. Fresh osteochondral grafts are utilized to resurface the head of the femur in Stages 3 and 4 in vigorous patients below the age of 60 when strong analgesics are required to relieve pain. A total hip arthroplasty is the treatment of choice for all patients in Stage 5 or those beyond the age of 60 in Stages 3 and 4. Five patients have had allografts; all are doing well. Three have been followed over 2 years, one over one and one-half years, and the other over 6 months. Twenty-three patients have had muscle pedicle grafts. The results have been good in the 8 patients in Stages 1 and 2. Only 5 of the 15 patients with osteonecrosis in Stages 3 and 4 have had good results.

Adult

Intraoperative femur fractures during total hip replacement.

Eleven intraoperative femur fractures occurred during 605 total hip replacements at Rancho Los Amigos Hospital, an incidence of 1.8%. Fractures occur more often in women, are usually located in the proximal femur, and mostly occur during femoral reaming. The main predisposing factors were osteoporosis and previous hip operation. The treatment may be operative or non-operative depending on the location and type of fracture. This complication is associated with a high morbidity and a significant delay in convalescence.

Adult