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Biomedical subjects

M H Noweir

Publications and source records attributed to M H Noweir.

At least 19 recordsLinked to original sources

Study of noise pollution in Jeddah hospitals.

The present study was conducted on a sample of 6 hospitals in Jeddah to investigate the status of noise pollution there, and as related to community background noise, operational activities, hospital size and operational concepts (public vs private). Generally, the levels of noise in the clinics, patient rooms, offices, waiting areas and corridors significantly exceed the recommended standard. The noise levels in the machinery rooms significantly exceed the levels in offices, waiting areas and corridors which, in turn, significantly exceed the levels in clinics and patient rooms. Background community noise has a little impact on indoor noise due to the construction characteristics of the hospitals' buildings. However, "operational noise" from machinery and from the move of public (patients, attendants and employees) significantly contribute to indoor noise. Proper site location, city planning, traffic engineering, building construction, equipment selection, construction and equipment maintenance, and system management have been recommended for the abatement of hospital noise pollution.

Health Facility Environment↗

A comparative environmental and medical study of dust exposure in jute and cotton mills in Burma.

Jute is extensively cultivated and processed in Burma, as well as "lower-grade" cotton. This study was conducted there to compare dust exposure in jute and cotton mills, to study the acute and chronic effects of dust exposure on workers, and to establish exposure-response relationship. A sample of 799 male and female workers in two jute mills and two cotton textile mills, as well as a control group of 153 matching subjects, was examined, and dust exposure in the work environment was evaluated. Very high dust concentrations existed in the early stages of jute processing and sorting, which were reduced when jute fibers got cleaner, as in drawing and spinning, and were related to the grade of the processed fiber. Much lower concentrations of dust existed in the cotton mills, but exceeded the TLV (ACGIH) only in opening and cleaning and in carding operations. However, byssinosis occurred only in workers exposed to cotton dust, particularly among males, and its prevalence was related to the level and duration of dust exposure. Chronic bronchitis, cough and wheezing occurred at higher rates among all workers than in the control, while irritation to nose and throat, eyes and skin prevailed only among jute workers. A significant reduction in FVC, FEV1.0 and PEF (before and during shift) was observed in workers compared to control subjects, and was related to workers' exposure and age; however, this reduction was not related to symptoms of different respiratory conditions. "Cheroots" smoking was found to be an important potentiating factor in the occurrence of non-specific respiratory diseases and reduction in FEV1.0, particularly among jute workers.

Adult↗

An environmental and medical study of byssinosis and other respiratory conditions in the cotton textile industry in Egypt.

This study was conducted in a typical Egyptian textile plant located in Alexandria. Male workers from all operations (N = 506) were examined and their dust exposures were assessed. Results showed that airborne dust concentrations were very high and that the plant fraction is mostly concentrated in respirable dust. Byssinosis prevailed in 21% of workers in opening and cleaning sections and in 13% in carding and combing rooms, but was found in none of the workers in drawing, twisting, and spinning operations, in only 1.1% in weaving, and in 3.1% of workers in other "auxiliary" occupations. The rare prevalence of byssinosis among the latter workers' groups was attributed to the workers' continuous exposure without fixed weekend interruption, the personal and family history of exposure to cotton, the low proportion of plant materials in dust evolved in related operations, the fine quality of Egyptian cotton, and/or the population characteristics of Egyptian workers. Reduction in FEV 1.0 at the end of the first work shift after absence from work occured more often than byssinosis, which indicates the importance of this test for the early detection of effects of cotton dust exposure. It is suggested that a nationwide study in the cotton textile industry is indicated.

Adult↗

Role of histamine in the aetiology of byssinosis. I Blood histamine concentrations in workers exposed to cotton and flax dusts.

The formation or the accumulation, or both, of histamine in the lungs may be potentiated by agent(s) present in cotton dust at higher level(s) than in flax dust and negligible in cottonseed dust. It has been suggested that such potentiation may be due to the activation of the ability of the lung to produce histamine and/or produce or recruit mast cells; this may present an acceptable explanation of the mechanism by which the propagation of the chronic effect of the dust proceeds in cotton and flax workers. Histamine accumulated in the lung over the weekend is released on exposure to dust causing the symptoms of byssinosis. The difference in the rate of histamine metabolism relative to the rate of histamine formation in byssinotic subjects leads to a more prolonged histamine accumulation than in symptom free subjects, with the consequent appearance of the symptoms of byssinosis. Continuous exposure to dust, without weekend interruption, leads to equivalent rates of histamine formation and metabolism with non-considerable histamine accumulation in the lungs and consequent absence of the symptoms of byssinosis.

Bronchitis↗

Role of histamine in the aetiology of byssinosis. II. Lung histamine concentrations in guinea pigs chronically exposed to cotton and flax dusts.

Data presented in this study support the finding that cotton and flax dusts contain agents which potentiate the formation or accumulation of histamine or both in the lungs of guinea pigs exposed to dust, and that such agents are present at much higher levels in cotton dust than in flax dust. The potentiating effect may be through the recruitment of mast cells into the lung. Both cotton and flax dusts contain methylating enzyme inhibitory agents, whereas cotton dust also contains agents that inhibit histaminase activity; flax dust contains agents potentiating histamine activity. These agents working together result in the accumulation or depletion of histamine observed in the different groups of animals exposed to either cotton or flax dust in this study.

Animals↗

Some observations on epidemiologic studies in Egyptian gins, cotton pressing plants and cottonseed oil extraction plants.

The follow-up studies presented in this report wee conducted to evaluate the impact of the relative technical improvements that took place in the cotton processing industries of Egypt in the last 10-15 years on the health of the workers. Results have indicated tha: 1) the health status of the workers has been relatively improved; however, their work environment is far from being safe. 2) The prevalence of byssinosis and reduction in FEV1 during the first day of work after the weekend are related to the duration of exposure, level of dustiness and content of plant debris in dust. 3) Chronic effect of exposure to cotton dust, demonstrated as reduction in predicted FVC, develops in workers continuing exposure for long durations, even if the classic symptoms of byssinosis and reduction in FEV1 do not occur. 4) Women workers are more liable to be affected by cotton dust exposure than the men. 5) "Cottonseed dust" may not be a "byssinnogenic" dust; however, it is capable of producing ventilatory function effects similar to those produced by cotton dust.

Adolescent↗

Role of family susceptibility, occupational and family histories and individuals' blood groups in the development of silicosis.

A previous investigation has shown that family susceptibility and occupational and family histories have a decisive role in the development of byssinosis among workers exposed to flax dust. Results of investigation of silicosis in 814 male workers exposed to silica-bearing dust showed that family susceptibility has an important role in the development of silicosis among examined workers, and workers whose fathers had an occupational history of exposure to silica-bearing dust were more resistant to the development of the disease than those with non-exposed fathers. The degree of consanguinity of parents and individuals' blood groups, also, have a role. Workers with cousin parents were relatively highly susceptible to the development of silicosis as well as workers with blood groups "O" or "AB". It has been concluded that the investigated factors might have a role in the development of other occupational diseases and further investigations are indicated.

ABO Blood-Group System↗