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Biomedical subjects

M H Seelenfreund

Publications and source records attributed to M H Seelenfreund.

At least 19 recordsLinked to original sources

The effect of normal childbirth on eyes with abnormalities predisposing to rhegmatogenous retinal detachment.

BACKGROUND: Pregnant women who have high myopia, a history of retinal detachment or retinal holes, or have known lattice degeneration are frequently referred to an ophthalmologist for advice concerning the management of pregnancy and labor, i.e. whether a spontaneous vaginal delivery can be allowed and whether prophylaxis for high-risk retinal pathology is indicated. Many obstetricians still believe that pregnant women with ocular abnormalities predisposing to rhegmatogenous retinal detachment should have an instrumental delivery, and a few even advocate cesarian section. Very little has been written about the management of pregnant women with high-risk retinal pathology, and opinions differ considerably. Patient data on this subject are scarce. METHODS: We studied 10 women who had 19 deliveries (10 prospective and 9 retrospective) and who had a history of retinal detachment, had been diagnosed as having extensive lattice degeneration, or had been treated for symptomatic retinal holes or breaks. The women were followed from the third trimester of pregnancy through labor and delivery into the postpartum period, looking for changes in the retinal status. RESULTS: We found no changes in the retinal status in the postpartum examination. CONCLUSION: We conclude that prenatal treatment of asymptomatic retinal pathology is not indicated and that spontaneous vaginal delivery may be allowed to take place in women with high-risk retinal pathology.

Adult↗

Legal aspects of work-related eye injuries.

As court-appointed medical advisors in the speciality of ophthalmology for the Israeli Labour Courts, we are called upon to assist in making decisions on work-related eye injuries or illnesses. In this report we present seven cases of eye injuries which workers claimed were caused by work accidents. Each case helps to illustrate the various guidelines we use in making a medical judgement as to whether or not a specific ocular problem was, indeed, the result of a work accident.

Accidents, Occupational↗

Essential thrombocythemia: a rare case of central retinal artery occlusion.

Essential thrombocythemia is a myeloproliferative disorder with an increased amount of abnormal platelets, causing both hemorrhagic and thrombotic pathology. Some of its systemic complications include deep vein thrombosis, pulmonary emboli, myocardial infarcts, and renal vessel thrombosis among others. We present the rare case of a woman suffering from essential thrombocythemia with the sudden loss of vision in her right eye, caused by central retinal artery occlusion. A possible connection between these two disorders is discussed.

Aged↗

Mitral valve prolapse (Barlow's syndrome) and retinal emboli.

Mitral valve prolapse (M.V.P.) is a noninflammatory degeneration of the mitral valve leaflets which results in a billowing of the redundant valve tissue toward the left atrium during the systolic phase. Mitral valve prolapse can be diagnosed by echocardiography or by auscultation where a characteristic mid-systolic click and late systolic murmur can be heard. Ophthalmic complications of MVP include chronic external progressive ophthalmoplegia and an association with keratoconus. In this case we present a case of a young woman who presented with sudden recurrent decrease in vision secondary to retinal arterioli emboli associated with the mitral valve prolapse syndrome.

Adult↗

A metabolic analysis of high myopia and senile macular degeneration.

Abnormal zinc and copper metabolism have been described in several retinal disorders affecting the retinal pigment epithelium. An infrequent presentation of senile macular degeneration in high myopia is well known. We examined the blood for zinc and copper and the urine for copper of three groups of patients, one consisting of high myopia, another with high myopia and primary retinal detachment and the other a group of patients with senile macular degeneration. When comparing the above groups of patients, we found statistically elevated values of serum zinc (p = less than 0.005) in the group of patients with senile macular degeneration. The significance of these findings, and a correlation with the pathogeneses of high myopia and senile macular degeneration is discussed.

Adult↗

A new sling material for ptosis patients.

Patients with poor or total absence of levator function require correction of their ptosis by a sling procedure. The aim of the procedure is to utilize the action of the frontalis muscle, innervated by the seventh nerve, to mechanically raise the droopy eyelid. The most common materials used for the sling are autogenous or preserved fascia lata and synthetic products such as nylon or dacron sutures. We introduce a new material for the sling procedure--preserved placental umbilical vein modified for the use as a sling. Two cases are presented in which this material was used with excellent results.

Adolescent↗

Copper and zinc metabolism in high myopic patients with retinal detachment evaluation of the Cu/Zn ratio.

In a previous work abnormalities in the copper and zinc metabolism in high myopic patients were found. Primary Retinal Detachment is a common complication of High Myopia. In order to establish further their relationship, a study of the metabolism of these metals was performed in myopic patients with Retinal Detachment. A significant high copper and zinc concentration in the urine of these patients was found. An inverse ratio of copper and zinc between their concentration in the subretinal fluid and their concentration in serum was present as well. The significance of these findings and their connection to the Retinal Pigment Epithelium is discussed.

Adult↗

Recurrent tears following successful retinal detachment surgery.

In 17 cases of recurrent retinal tears occurring after successful retinal detachment surgery, the new tears developed on or near the treated primary tear in seven cases and away from the treated tear in ten cases. It took an average of 25.6 months for the second tears to develop, and almost all of the recurrent tears were the same distance from the limbus as the primary tear. The benefit of the 360 degree encircling band and the relationship of the thermal injury to production of a second tear is discussed.

Adult↗

Branch retinal artery occlusion in patients with Hodgkin's disease.

Ocular involvement in Hodgkin's disease is relatively unusual. This report describes two cases of branch retinal artery occlusion in young patients with Hodgkin's disease. Both patients were thought to be in remission when the occlusions occurred. The possible etiology and relationship to drug therapy is discussed.

Adult↗

Retinal tears with total vitreous hemorrhage.

In ten cases of nontraumatic retinal tears with initial vitreous hemorrhages so dense that all retinal detail was obscured, medical management included hospitalization, sedation, and binocular patching. It took an average of 4.3 days for the vitreous to clear so that the tears could be examined. All the tears were on or anterior to the equator, and all were in the superior quadrants. Surgery was performed promptly once the tears were visible even though much of the retina was still covered with hemorrhage. After total clearing of the vitreous, no additional retinal tears were found in any of the ten cases. Postoperative complications included hemorrhages in three cases, macular pucker in one case, and a paramacular star in one case.

Adult↗

Absorbable implants in nondrainage procedures for repair of retinal detachment.

Our experience in 1,700 consecutive cases of retinal surgery for the repair of nontraumatic, rhegmatogenous retinal detachments using a modified technique involving a nondrainage procedure with an absorbable implant was presented. We found that 228 of these 1,700 cases fell into our criteria for the use of this technique. We discussed the indications and contraindications for both the operative procedure and for the absorbable implant, and it is our belief that this technique is a valuable addition to the methods available to the retinal surgeon for the treatment of certain selected cases of retinal detachment.

Drainage↗

Retinal injuries associated with cataract surgery.

Five patients had trauma to the retina that occurred during cataract surgery. In two of the cases the injury was caused by perforation of the globe by the retrobulbar injection needle and in one case the retinal injury occurred when the superior rectus muscle bridle suture perforated the sclera. A stab incision for release of blood in an expulsive choroidal hemorrhage caused a retinal dialysis. Another case of retinal dialysis was caused by aspiration of solid vitreous after vitreous loss.

Adult↗

Long-term follow-up of scleral buckling procedures with sickle cell disease and retinal detachment treated with the use of hyperbaric oxygen.

We have presenteed a late follow-up study of 8 eyes previously presented which were treated with scleral buckling procedures under hyperbaric oxygen conditions for repair of rhegmatogenous retinal detachments complicating sickle cell disease. In addition, we have presented a patient treated under similar conditions with a scleral shortening procedure and drainage of subretinal fluid for repair of a non-rhegmatogenous traction detachment secondary to diabetic retinopathy and sickle disease. We feel that our successful results in these cases and our lack of the usually reported complications merits the continued use of this technique in these difficult cases of detachment of the retina.

Adult↗