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Biomedical subjects

M H Soiderer

Publications and source records attributed to M H Soiderer.

7 recordsLinked to original sources
PubMed1989

Prostatic intraepithelial neoplasia: a lesion that may be confused with cancer on prostatic ultrasound.

Most prostatic adenocarcinomas reveal a hypoechoic peripheral zone lesion on transrectal ultrasonography. Numerous benign processes can have similar transrectal ultrasound findings. We report 8 cases of transrectal ultrasound-guided prostatic biopsies of peripheral zone hypoechoic lesions that demonstrated prostatic intraepithelial neoplasia, a presumed premalignant lesion. Immunohistochemistry using an antibody directed against cytokeratins 5 and 14 was performed to exclude carcinoma. Of the men 2 had invasive carcinoma on repeat biopsy and 1 had carcinoma diagnosed on subsequent transurethral resection. Patients with prostatic intraepithelial neoplasia on biopsy of hypoechoic peripheral zone lesions merit careful monitoring.

Adenocarcinoma↗
PubMed1987

Needle aspiration and core biopsy of prostate cancer: comparative evaluation with biplanar transrectal US guidance.

Biplanar, transrectal ultrasound (US) guidance of needles was used in the transperineal biopsy of possibly malignant prostatic lesions in 80 patients (83 biopsies). A 22-gauge cytologic needle was used to locate and fixate the lesion, and aspiration specimens for cytologic and histologic evaluation were obtained (with 22- and 14-gauge needles, respectively). Twenty-one 19-gauge needle core biopsies were also performed. Forty-nine patients (61%) had histologically prove adenocarcinoma. The rate of cancer diagnosis was 53% with cytologic evaluation and 54% with histologic evaluation (combined yield, 61%). This included 34% of cancers less than 1.0 cm in diameter and 56% of those 1.0-1.5 cm. Thirteen of 23 (57%) of these lesions were nonpalpable or equivocal on digital rectal examination. These results suggest that transrectal US guidance of thin-needle biopsies is useful in diagnosing early prostate cancer.

Adenocarcinoma↗
PubMed1983

Heterotopic gastric mucosa of the rectum. A rare cause of rectal bleeding.

We studied a patient with rectal gastric heterotopia and found nine reported cases of this rare disease in the literature. Symptoms include proctitis and rectal bleeding. Heterotopic gastric epithelium may be developmental or acquired, depending on the type of mucosal epithelium involved. Since this type of lesion can occur anywhere in the alimentary tract and even in multiple sites, long-term follow-up is recommended. The diagnosis is made by biopsy and pathologic examination. The treatment consists of total local excision. Sigmoidoscopy, colonoscopy, and technetium scanning can be used as adjunctive aids in diagnosing secondary sites of gastric heterotopia.

Adolescent↗
PubMed1975

Therapy questionably infarcted testis.

Observations made upon dogs and humans with apparent infarction of the testis secondary to torsion of the spermatic cord suggest that the treatment of choice for questionably viable testis is detorsion of the cord, replacement of the testis in its hemiscrotum, and fixation of the opposite testis. This form of therapy may be applicable to all "torsed testes" regardless of viability.

Animals↗