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Biomedical subjects

M H WEIL

Publications and source records attributed to M H WEIL.

At least 19 recordsLinked to original sources
PubMed1964

EXCESS LACTATE: AN INDEX OF REVERSIBILITY OF SHOCK IN HUMAN PATIENTS.

"Excess lactate," an indicator of oxygen debt, has been studied as a metabolic index of severity of the shock state in human patients. The levels of excess lactate correspond to severity of circulatory failure, and an excess of more than 4 millimoles per liter prognosticates a fatal outcome. The validity of this index was confirmed by studies on experimental hemorrhagic shock in dogs. It provides a parameter for measurement of "reversibility" and serves as an objective clinical guide.

Animals↗
PubMed1963

TREATMENT OF HYPERTENSION. THE SPECIAL PLACE OF ALPHA-METHYLDOPA. A SHORT TERM STUDY.

Alpha-methyldopa in amounts of 750 mg twice daily is an effective antihypertensive agent, intermediate in potency between reserpine-thiazide combinations and ganglionic-sympathetic blocking drugs. Because it produces few undesirable side effects, it is well accepted by patients.It is useful for patients with moderate or severe hypertension not controlled by reserpine-thiazide combinations. Its favorable action on cardiac output and renal blood flow provides special advantages for patients with advanced hypertension aggravated by cardiac or renal combinations.

Antihypertensive Agents↗