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Biomedical subjects

M Hájek

Publications and source records attributed to M Hájek.

At least 19 recordsLinked to original sources
PubMed1992

[Incisional, stab and gunshot wounds of the abdomen and thorax].

The authors give an account of the incidence and prognosis of the mentioned injuries treated during the past five years (1987-1991) at the surgical department of a district hospital in the centre of Prague. During the past two years a marked increase of these injuries was recorder. A total of 10 persons with abdominal injuries had ambulatory treatment and nine patients with injuries of the chest. During the same period 24 patients with abdominal injuries and 6 patients with chest injuries were hospitalized as well as four patients with combined abdominal and chest injuries. Nineteen ambulatory patients and 34 hospitalized patients during the five-year period are an ever increasing group of casualties who suffered injuries usually when drunk or due to violence.

Abdominal Injuries↗
PubMed1992

[3 years later].

Explore the source record for details and available documents.

Czechoslovakia↗
PubMed1991

[Initial clinical experience with the use of 31P MR spectroscopy in the examination of children with neuromuscular diseases].

31P MR spectroscopy (MRS) was used to investigate neuromuscular diseases of different origin in 35 patients, mostly children. After elaboration of the procedure of MR examination and evaluation of results the method of pattern recognition analysis was used. According to the results of 31P MR spectroscopy patients can be divided into three groups. Group A comprises patients with severe muscular lesions such as Duchenne dystrophy. The second group B is characterized by milder atrophic changes of muscle fibres. The third group comprises obscure cases. The 31P MRS method was also used for investigating the development of the disease in time--a drop of parameter PCR/Pi corresponds to a deterioration of the clinical condition of patients from group one. Maintenance of approximately the same values was observed in group B. An increase of PCR/Pi was also observed during administration of Prednisone in patients with child polymyositis.

Adolescent↗
PubMed1991

The phosphate pool of isolated dog heart during global ischaemia: comparison of two cardioplegic solutions with 31P NMR spectroscopy.

31P NMR spectroscopy was used to study the time course of changes in the concentration of high-energy metabolites and intracellular pH in the dog myocardium during hypothermic ischaemia at 9 degrees C in Bretschneider (HTK-B) and St. Thomas' Hospital (StTH) cardioplegic solutions. It was found that ATP and phosphocreatine degrade slowlier in HTK-B than in StTH, with phosphocreatine depletion occurring within 7.9 +/- 1.4 h in HTK-B and within 6.2 +/- 1.4 h in StTH. The values are virtually identical with the time intervals at which ATP concentration falls below the critical level (60% of initial ATP concentration). In agreement with biochemical analysis, a higher concentration of phosphomonoesters was noted until the 180th minute of ischaemia in HTK-B, a finding suggesting more rapid glycogen degradation in HTK-B. Even though HTK-B contains a high concentration of histidine buffer, higher values of intracellular pH were found during ischaemia in StTH. The effect of extracellular concentration of sodium ions on intracellular pH is discussed.

Adenosine Triphosphate↗
PubMed1990

[Manifestations of epidermolysis bullosa in the deglutition tract].

An account of a rare mucosal form of epidermolysis bullosa dystrophica in a 26-year-old female patient. The mucosal manifestations involved severe stenosis of the oral portion of the oesophagus. After exhausting all conservative therapeutic procedures (corticoids, transfer factor, dilatation), the stenosis of the oesophagus was successfully operated by resection of the stenotic portion and a plastic operation.

Adult↗