A new device preventing migration of epidural catheters.
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Biomedical subjects
Publications and source records attributed to M Hüttel.
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The adrenocortical response to a short tetracosactrin (Synacthen) test was studied in 11 patients receiving either etomidate infusion or thiopentone infusion used to maintain anaesthesia for abdominal hysterectomy. Pethidine was used as the narcotic component. The results showed that etomidate infusion (median 28.5 ug/kg/min) completely blocked the adrenocortical response to corticotropin stimulation for at least 24 h after surgery. No suppression was found in patients receiving thiopentone infusion. It is concluded that etomidate cannot be recommended for routine induction and maintenance of anaesthesia.
Variation of the stimulus intensity and duration over a wide range causes a change in amplitude of the c wave. If the energy of the applied stimulus is kept constant, however, stimuli of 0.05-4 s duration effected c waves that were nearly equal in amplitude. As patients consider shorter stimuli with higher intensities to be more comfortable in ERG recording, stimuli of a duration of 2-4 s seem most appropriate for clinical testing.
Visual evoked potentials were recorded sequentially, using permanent epidurally implanted electrodes, before and after accelerating the heads of rabbits. The amplitude of VEP, recorded after lesioning, was diminished and recovery time was prolonged depending on the amount of acceleration and the extent of brain lesions found later in histological examinations. VEP reflected damage to the brain more precisely than EEG or somatosensory evoked potentials, thus giving values for judging the extent of lesions in patients with brain injuries.
Antithrombin III activity and immunoreactive antithrombin III was determined in 31 patients before elective surgery and 3 h, 1, 3 and 7 d after. The values fell about 10--20% from 3 h to 3 d, but had returned to preoperative levels by the seventh day. A fall to 40% was seen. The fall in activity was a little smaller than the fall in immunoreactive protein.
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