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Biomedical subjects

M Hainsworth

Publications and source records attributed to M Hainsworth.

8 recordsLinked to original sources

Pressor responses to tracheal intubation after sublingual captopril. A pilot study.

The effect of sublingual captopril on the pressor response to intubation was studied in 40 patients. Captopril was used in one of two doses (12.5 mg and 25 mg) 25 minutes before tracheal intubation. Both doses were associated with a significant reduction in the pressor response to intubation (p less than 0.05) compared to placebo, but no significant difference existed between the two doses. Neither dose controlled changes in heart rate at intubation. Untoward hypotension occurred in the treatment groups. Caution is advised in the peri-operative use of angiotensin-converting enzyme inhibitors.

Administration, Sublingual↗

Tuberculosis of the conjunctiva occurring in association with a neighbouring lupus vulgaris lesion.

A case of tuberculosis of the conjunctiva in association with a neighbouring lupus vulgaris lesion is reported. Both lesions resolved within one month of starting antituberculous therapy. Tuberculosis of the conjunctiva is nowadays a rare condition. It should be considered in the differential diagnosis of any unusual chronic conjunctivitis, particularly in patients who are at risk of contracting tuberculosis.

Adult↗

HIV surveys in KwaZulu.

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Acquired Immunodeficiency Syndrome↗

Pancreatic somatostatinoma: presentation with recurrent episodes of severe hyperglycaemia and ketoacidosis.

A 47-year-old woman was admitted on four occasions over a four-year period with severe hyperglycaemia associated with marked ketoacidosis. She had weight loss with hepatomegaly and ultrasonography indicated a pancreatic tumour which was shown to be a somatostatinoma. Resection resulted in prolonged survival. The biochemical and morphological features of this rare tumour are presented, and an explanation for the unusual presentation of a somatostatinoma with episodes of ketoacidosis is given.

Adenoma, Islet Cell↗

The fluorescence of melanocytic lesions.

The fluorescence of routine formalin-fixed sections of a variety of melanocytic lesions has been studied. The technique has value in distinguishing benign and atypical nevi from malignant melanomas. Forty-one of 48 melanomas exhibited positive fluorescence, whereas 15 of 86 of a variety of benign nevi were positive. The majority of the negative melanomas were Hutchinson's melanotic freckles, and the majority of the positive nevi were Spitz's nevi. Positive focal junctional fluorescence was a feature in up to half of the cases from established dysplastic nevus syndrome, but was noted only occasionally in sporadic dysplastic nevi. This distinguishes the dysplastic group from banal nevi and may be a marker of malignant potential. It is proposed that positive fluorescence is a marker of a melanocyte with an immature metabolic pathway.

Adolescent↗

[Not Available].

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Demography↗

Women in grief.

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Adaptation, Psychological↗